Under the conditions of constant informational-psycho-emotional pressure in modern society, maintaining an optimal level of cognitive performance and neuronal well-being acquires critical importance. Traditional methods of cognitive optimisation are often oriented solely toward short-term stimulation, overlooking the brain’s fundamental need for cyclical recovery. The present study conducts a scientific analysis of the innovative two-phase nootropic formula AM/PM Brain Booster, developed in accordance with natural circadian rhythms. The aim of the work is the systematic evaluation and verification of the chronobiological approach in neuronutriceutics using this complex as an example. The methodology includes an examination of the component composition, an investigation of synergistic interactions among ingredients, and a review of existing clinical trials in the context of current scientific publications. The results demonstrate that separation into a morning (AM) formula, which activates cognitive functions, and an evening (PM) formula, directed toward neuroregeneration, provides a comprehensive influence ranging from enhanced attention and stress resilience to increased synaptic plasticity and improved sleep quality. The conclusions confirm the hypothesis that the two-phase system surpasses monophasic stimulants in long-term neuroprotection and maintenance of cognitive health. The presented material will be of interest to neurobiologists, preventive-medicine specialists, nutritionists, and other researchers striving to optimise mental performance.

nootropics, cognitive functions, circadian rhythms, neuroprotection, adaptogens, magnesium L-threonate, NGF, synaptic plasticity, stress, sleep quality

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