The article discusses the scientific foundations and practical technologies of combined ultrasonic and infrared hair treatment to restore and improve performance. It has been shown that acoustic cavitation in the frequency range of 20-40 kHz leads to mechanical and chemical destruction of the disulfide bonds of keratin, increasing the access of therapeutic compounds to the cortical layer of the hair. Infrared radiation (800-1200 nm) provides controlled heating and "sealing" of cuticle scales, which helps to preserve the improved properties of the fiber. The prospects for further optimization of processing parameters, the development of new nanoformules based on keratin hydrolysates, as well as the possibility of introducing the technique into salon and home practice are discussed. The information presented in the article will be of interest to specialists in the field of trichology and dermatological biophysics who study the molecular and structural mechanisms of the interaction of acoustic and photonic fields with the keratin matrix of the hair and develop innovative therapeutic protocols for alopecia and other hair pathologies. The practical value of the material is also obvious for clinical cosmetologists and developers of high-tech care products focused on integrating controlled physical methods of exposure into aesthetic procedures and pharmaceutical formulas to optimize hair regeneration and strengthening.

It was found that Mandels medium was optimal for T. harzianum 55, and Capek medium was optimal for T. harzianum 54, T. asperellum 12. However, in order to increase the production of phytohormones by these strains, the composition of the medium was changed to enrich and reduce the cost of the medium. That is, Mandels and Capek mediums were prepared with 2% sucrose and 2% other carbon sources (molasses, cottonseed meal, crushed cotton leaves and corn extract) added, the strains were grown in them, and the production of GC and Indole complexes was studied. It was found that all three strains produced the most active GC and Indole complexes in mediums enriched with corn extract and molasses. In the control variant, it was found that in these nutrient media, the amount of indole compounds synthesized by T. harzianum 55 was 0.559 mg/ml and the amount of GC was 0.172 mg/ml, the amount of indole compounds synthesized by P. Canescens 54 was 0.418 mg/ml, the amount of GC was 0.189 mg/ml, and the amount of indole compounds synthesized by F. moniliforme 12 was 0.518 mg/ml and the amount of GC was 0.194 mg/ml.

Long-term care facilities face a dual systemic strain: widespread comorbidity of mental disorders among residents and a high volume of preventable hospitalizations, which collectively imposes an excessive burden on healthcare. The aim of the study is to provide a theoretical rationale and present a comprehensive modular program that integrates psychotherapeutic and psychosocial interventions into the routine practice of nursing homes, focusing on improving residents’ mental well-being and reducing hospitalization rates. The research methodology is based on a systematic literature review with analysis of results from large clinical programs (OPTIMISTIC, WHELD), as well as a descriptive analysis of a case study reflecting the practical implementation of the authors’ model across diverse contexts — from nursing homes in the United States to centers for elderly refugees in humanitarian crisis settings. The data obtained indicate that the integration of psychotherapy, personalized dementia care, proactive care pathway planning, and the Treat-in-Place model reduces the severity of anxiety and depressive symptoms (by 30–40% in pilot samples) while simultaneously decreasing the proportion of preventable hospitalizations by 19–25%. In conclusion, the proposed model is a scientifically validated and practically tested solution capable of transforming the long-term care system, improving the quality of life of older adults, and rationalizing healthcare expenditures. The material is intended for leaders of long-term care institutions, clinical psychologists, geriatricians, and healthcare organization specialists.