WAYS TO IMPROVE THE EFFECTIVENESS OF CHEMOTHERAPY PATIENTS WITH LARYNGEAL CANCER, WITH MALIGNANT TUMORS OF THE NOSE AND PARANASAL SINUSES
Ulmasov Firdavs Gayratovich , Samarkand State Medical University, Uzbekistan Rakhimov Zhakhongir Khotamovich , Samarkand State Medical University, Uzbekistan Nasretdinova Makhzuna Takhsinovna , Samarkand State Medical University, UzbekistanAbstract
At present, when planning complex treatment of patients with¬malignant tumors, an increasing role is given to chemotherapy. More than 50 antitumor chemotherapy drugs are used in clinical practice¬. This is due to the fact that neoplasms¬of different localization have different sensitivity to drugs. It was also found that they differ in their sensitivity to antitumor cytostatic agents in the same localization, prevalence, and histological structure¬. If the primary tumor focus in the head and neck area and metastases to regional lymph nodes, depending on the stage, can often be eliminated by radiation, surgical or combined treatment, then stable and long-term remission¬is ensured by the use of adjuvant chemotherapy.
Keywords
complex¬treatment, complex treatment, regional intra-arterial chemotherapy
References
Lund VJ, Howard D, Wei W. Tumours of the nose, sinuses and nasopharynx. Thieme 2014;1–595
Edge SB, Compton CC, Fritz AG, Greene FL, Trotti A. AJCC Cancer Staging Manual, 7th edn. New York: Springer, 2010
Dragonetti A, Gera R, Sciuto A, Scotti A, Bigoni A, Barbaro E et al. Sinonasal inverted papilloma: 84 patients treated by endoscopy and proposal for a new classification. Rhinology 2011;49:207–13
Nicolai P, Berlucchi M, Tomenzoli D, Cappiello J, Trimarchi M, Maroldi R et al. Endoscopic surgery for juvenile angiofibroma: when and how. Laryngoscope 2003;113:775–82
Ganly I, Patel SG, Singh B, Kraus DH, Bridger PG, Cantu G et al. Craniofacial resection for malignant paranasal sinus tumors: report of an international collaborative study. Head Neck 2005;27:575–84
Snyderman CH, Carrau RL, Kassam AB, Zanation A, Prevedello D, Gardner P et al. Endoscopic skull base surgery: principles of endonasal oncological surgery. J Surg Oncol 2008;97:658–64
Lund V, Stammberger H, Nicolai P, Castelnuovo P, Beal T, Beham A et al. European position paper on endoscopic management of the nose, paranasal sinuses and skull base. Rhinol Suppl 2010;22:1–144
Lund V, Wei W. Endoscopic resection of malignant sinonasal tumors: an eighteen year experience. Rhinology 2015;40:407–11
Nicolai P, Battaglia P, Bignami M, Bolzoni Villaret A, Delu G, Khrais T et al. Endoscopic surgery for malignant tumors of the sinonasal tract and adjacent skull base: a 10-year experience. Am J Rhinol 2008;22:308–16
Eloy J, Vivero R, Hoang K, Civantos FJ, Weed DT, Morcos JJ et al. Comparison of transnasal endoscopic and open craniofacial resection for malignant tumors of the anterior skull base. Laryngoscope 2009;119:834–40
Batra P, Luong A, Kanowitz SJ, Sade B, Lee J, Lanza DC et al. Outcomes of minimally invasive endoscopic resection of anterior skull base neoplasms. Laryngoscope 2010;120:9–16
Devaiah AK, Andreoli MT. Treatment of esthesioneuroblastoma: a 16-year meta-analysis of 361 patients. Laryngoscope 2009;119:1412–16
Rimmer J, Lund V, Beale T, Howard D, Wei W. Olfactory neuroblastoma – a 35 year experience and suggested follow-up protocol, Laryngoscope 2014;124:1542–49
Lund VJ, Chisholm EJ, Howard DJ, Wei WI. Sinonasal melanoma: a review of 115 cases assessing outcomes of surgery, postoperative radiotherapy and endoscopic resection. Rhinology 2012;50:203–10
Zanation A, Ferlito A, Rinaldo A, Gore M, Lund V, Mckinney K et al. When, how and why to treat the neck in patients with esthesioneuroblastoma: a review. Eur Arch ORL 2010;267:1667–71
Ang KK, Garden AS. Radiotherapy for Head and Neck Cancer: Indications and Techniques, 3rd edn. Lippincott, 2006
Shakhanova Sh. Sh., Rakhimov M. N. Aspects of sarcopenia syndrome in oncological practice: diagnosis and treatment (literature review) // Journal of Biomedicine and Practice. 2023, vol. 8, issue 3, pp. 406-417
18.Rakhimov M. N., Tulanov T. B., Shakhanova Sh. Sh., Aslsnova M. L. Pathogenetic aspects of cancer anorexia// Journal of Biomedicine and Practice. 2023, vol. 8, issue 4, pp.192-201
Dirix P, Vanstraelen B, Jorissen M, Vander Poorten V, Nuyts S. Intensity-modulated radiotherapy for sinonasal cancer: improved outcome compared to conventional radiotherapy. Int J Radiat Oncol Biol Phys 2010;78:998–1004
Shakhanova Sh. Sh., Rakhimov N. M., & Murodov Sh. T.. (2024). Aspects of sarcopenia syndrome in oncological practice: diagnosis and treatment. The American Journal of Medical Sciences and Pharmaceutical Research, 6(02), 16–25. https://doi.org/10.37547/TAJMSPR/Volume06Issue02-03
Bristol IJ, Ahamad A, Garden AS, Morrison WH, Hanna EY, Papadimitrakopoulou VA et al. Postoperative radiotherapy for maxillary sinus cancer: long term outcomes and toxicities of treatment. Int J Radiat Oncol Biol Phys 2007;68:719–30
Brasnu D, Laccourreye O, Bassot V, Laccourreye L, Naudo P, Roux FX. Cisplatin-based neoadjuvant chemotherapy and combined resection for ethmoid sinus adenocarcinoma reaching and/or invading the skull base. Arch Otolaryngol Head Neck Surg 1996;122:765–68
20. Dulguerov P, Allal AS. Nasal and paranasal sinus carcinoma: how can we continue to make progress? Curr Opin Otolaryngol Head Neck Surg 2006;14:67–72
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