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DOI: The Content Of Vitamin D Metabolites In Rachit In Children Of Early Age Who Received Specific Prevention
Rasuljon Mamasiddikovich Shermatov , Candidate Of Medical Sciences, Head Of The Department Of Pediatrics, Fergana Medical Institute Of Public Health, Uzbekistan Zebo Xamroevna Nishanova , Assistant Of The Department Of "Pediatrics" Of The Fergana Medical Institute Of Public Health, Uzbekistan Mavlonjon Ziemiddinovich Nasirdinov , Assistant Of The Department Of "Normal And Pathological Physiology" Of The Fergana Medical Institute Of Public Health, Uzbekistan Shoxrux Ravshanjon Ogli Xabibullayev , Assistant Of The Department Of "Normal And Pathological Physiology" Of The Fergana Medical Institute Of Public Health, Uzbekistan Sardorbek Solijon Ugli Bobojonov , Assistant Of The Department Of "Normal And Pathological Physiology" Of The Fergana Medical Institute Of Public Health, UzbekistanAbstract
52 patients with rickets and 10 healthy children were examined. Among patients with rickets, 35 children were born in women with a complicated course of pregnancy (threat of termination, toxicosis of the first and second half). In 12 children, mothers had chronic liver and kidney diseases before giving birth.
The level of 25(OH) vitamin D (25-oxycalciferol) and 24.25 (OH)2 vitamin D (24.25-dioxycalciferol) was determined. The content of calcium-regulating hormones in the blood serum was determined by radioimmunological analysis. To assess the severity of the rickets process, the activity of alkaline phosphatase in the blood serum was determined using a standard kit.
The aim of our study was to determine the effect of specific prevention on the metabolism and course of the clinical form of rickets in young children.
Keywords
Rickets, vitamin D, vitamin D metabolism, specific prevention of rickets, parathyroid hormone, calcitonin, young children
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