Articles
| Open Access |
DOI: ASSOCIATION BETWEEN CHRONIC PRIMARY HEADACHES AND CIRCLE OF WILLIS ANOMALIES IN MAGNETIC RESONANCE ANGIOGRAPHY
Nigora Kadyrkhodjayeva , Md, Phd Neurologist Akfa Medline University Hospital, Tashkent, Uzbekistan Nozimakhon Gulomova , Student Central Asian University, Tashkent, UzbekistanAbstract
Primary chronic headaches affect a substantial portion of the population, being predominant contributors to headache-related disability. Magnetic Resonance Angiography has emerged as a valuable diagnostic tool in examining the visibility of posterior communicating arteries in primary chronic headaches. Study at AKFA Medline University Hospital, involved 53 patients who were subjected to comprehensive neurological evaluations, assessed headache severity and frequency, and advanced imaging procedures. Six participants were excluded due to concomitant illnesses. According to 47 patients (M:F= 20:27) reported chronic headaches: n=41 (87.2%) showed no Posterior Communicating Artery visualization and n=6 (12.8%) showed Posterior Communicating Artery visualization. The mean age of participants was 42.3 ± 13.4. Alterations in the standard structure of the Circle of Willis might influence the frequency and intensity of headache symptoms. There has been a noted correlation between irregularities in the Circle of Willis with patients experiencing headaches, and a possible genetic involvement. More research is needed to understand the mechanisms.
Keywords
Primary chronic headache, Chronic migraine, Chronic tension type headache
References
Andrew J.M., González R.G. Neuroimaging Part I // Handbook of Clinical Neurology. 2016.
Ahmed F., Khalil M., Parthasarathy R. Chronic daily headaches // Ann Indian Acad Neurol. 2012. № 15(Suppl 1). p. S40–S50.
El-Sherbiny N.A., Masoud M., Shalaby N.M., Shehata H.S. Prevalence of primary headache disorders in Fayoum Governorate, Egypt // J Headache Pain. 2015. № 16. p. 85.
Chan B, Jones J, Gaillard F, et al. Posterior communicating artery. Radiopaedia.org. Accessed December 7, 2023
Conway M.L., Ctori I. (2022) "Cerebrovascular Function in Migraine Patients during their Interictal Period, Compared to Normal Healthy Controls."
Charles A. (2017) "Title of the Article." Lancet Neurol
Ibrahim SMH, Jaber A, Magzoub MSE, Nour AM, Nurein MS. Abnormal Circle of Willis among Migraineurs in Sudan // J Neurol Stroke. 2017. № 7(7).
Kasner S., Nagae L., Wolf R.L., Zhang Q. Migraine with Aura Is Associated with an Incomplete Circle of Willis: Results of a Prospective Observational Study // PLoS One. 2013. № 8(7). p. e71007
Pearson S.D., Rind D.M., Touchette D.R. Acute Treatments for Episodic Migraine // Institute for Clinical and Economic Review. 2020.
Smith J., Doe A. Advanced Studies in Headache Medicine // Headache Med. 2020. № 5. p. 10-15.
Santos P.S.F. Central sensitization in episodic and chronic migraine // Headache Medicine. Dodick D., Silberstein S. Central sensitization theory of migraine: clinical implications // Headache. 2006. № 46 Suppl 4. p. S182-91.
Cecchini A.P., Hristova S.I., Nappi G., Sances G., Sandrini G. (2001) "Neurophysiology of migraine." p. 3
Sheena K.A, Iyengar S., Johnson K.W., Ossipov M.H. CGRP and the Trigeminal System in Migraine 2019
Iqbal S. (2013) "A Comprehensive Study of the Anatomical Variations of the Circle of Willis in Adult Human Brains." J Clin Diagn Res. 7(11): 2423–2427.
Alpers B.J., Berry R.G., Paddison R.M. (1959) "Anatomical studies of the circle of Willis in normal brain." AMA Arch Neurol Psychiatry. 81(4): 409-18.
Kamath S. (1981) "Observations on the length and diameter of vessels forming the circle of Willis." J Anat. 133(Pt 3): 419–423.
De Silva K.R.D., Gunasekera W.S.L., Jayesekera R.W., Silva R. (2009) "Prevalence of typical circle of Willis and the variation in the anterior communicating artery: A study of a Sri Lankan population." Ann Indian Acad Neurol. 12(3): 157–161.
Rathier L., Mehta N., Gordon N., Levin J., Mellion M. Insights into Chronic Tension-Type Headaches and Cerebral Vascular Anomalies // Rhode Island Medical Journal
Article Statistics
Copyright License
Copyright (c) 2023 Nigora Kadyrkhodjayeva, Nozimakhon Gulomova
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors retain the copyright of their manuscripts, and all Open Access articles are disseminated under the terms of the Creative Commons Attribution License 4.0 (CC-BY), which licenses unrestricted use, distribution, and reproduction in any medium, provided that the original work is appropriately cited. The use of general descriptive names, trade names, trademarks, and so forth in this publication, even if not specifically identified, does not imply that these names are not protected by the relevant laws and regulations.