Articles
| Open Access |
DOI: Features Antihypertensive Therapy Obesity
Ishankulova Nasiba Nurmamadovna , Department Of Internal Diseases No. 1. Samarkand State Medical Institute, Uzbekistan Abdushukurova Komila Abdurasulovna , Department Of Internal Diseases No. 1. Samarkand State Medical Institute, UzbekistanAbstract
Obesity negatively affects structure of renal tissue and increases the risk of developing renal failure and progression arterial hypertension. Adipose tissue is also a source of synthesis of all components renin-angiotensin system and can actively produce angiotensin.
Keywords
Obesity, antihypertensive therapy,
References
Nedogoda S.V. Obesity and arterial hypertension: theory and practice of choosing the optimal antihypertensive drug. M .: Medikom, 2012.
Bergman RN, Van Citters GW, Mittelman SD et al. Central role of adipocyte in the metabolic syndrome. J Invest Med 2001
Chu NF, Spiegelman D, Hotamisligil GS et al. Plasma insulin, leptin, and soluble TNF receptors levels in relation to obesity-related atherogenic and thrombogenic cardiovascular disease factors among men. Atherosclerosis 2001,
Drenick EJ, Bale GS, Seltzer F, Johnson DG. Excessive mortality and cause of death in morbidly obese men. JAMA 1980,
Esler M The sympathetic system and hypertension. Am J Hypertens, 2000,
Gorzelniak K, Engeli S, Janke J et al. Hormonal regulation of the human adipose-tissue renin-angiotensin system: relationship to obesity and hypertension. J Hypertens, 2002,
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