Articles
| Open Access |
DOI: Molecular Genetic Factors Of Breast Cancer Development (Review)
Abdulla Nusratillayevich Abdukhakimov, Muqaddas Tukhtabievna Tukhtaboeva , Tashkent Regional Branch Of The Republican Specialized Scientific And Practical Medical Center Of Oncology And Radiology, Tashkent, UzbekistanAbstract
The problem of timely detection of breast cancer is not only in its asymptomatic
development, but also in the absence of reliable diagnostic markers that contribute to the
early detection of the neoplastic process. The main objectives of oncogenomics are to
study the molecular mechanisms of carcinogenesis and develop optimal methods for
preventing, diagnosing and monitoring cancer. One approach to solving this problem is to
analyze the epigenetic characteristics of the tumor genome.
Keywords
: breast cancer, heredity
References
Vanyushin B.F. Epigenetics today and tomorrow // Vavilov Journal of Genetics and
Selection. - 2013. - No. 17 (4/2). - S. 805-832. 12
Imyanitov E.N., Hanson K.P. Molecular Oncology: Clinical Aspects. - St. Petersburg,
.-- 211 p. 4
Kazubskaya TP, Loginov V.I., Khodyrev D.S., Ermilova V.D., Payanidi Yu.G.,
Chkhikvadze N.V., Selchuk V.Yu., Braga E.A. Methylation of genes RASSF1A, RARβ2,
SEMA3B in epithelial tumors of the mammary gland, ovaries and polyneoplasia // Tumors
of the female reproductive system. - 2012. - No. 1. - S.61-68. 6
Kazubskaya T.P., Khodyrev D.S., Pronina I.V., Ermilova V.D., Payanidi Yu.G.,
Chkhikvadze N.V., Selchuk V.Yu., Braga E.A., Loginov V.I. Methylation of suppressor
genes in epithelial tumors of the mammary gland and ovaries, including primary multiple
// Russian Biotherapeutic Journal. - 2012. - No. 1. - Volume 11. - P.69-74.-3
Laptiev SA, Korzhenevskaya MA, Imyanitov EN Molecular genetic "portrait" of breast
cancer. Scientific notes of St. acad. I.P. Pavlova. 2017; 24 (2): 12-22. DOI: 10.24884 /
-4181-2017-24-2-12-22.
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