Articles | Open Access | DOI: https://doi.org/10.37547/TAJMSPR/Volume03Issue09-08

Morphological Characteristics Of The Kidney In Chronic Alcoholism

Hamrayev Izzat Sayfullaevich , Surgeon, The Department Of General Surgery, Republican Emergency Center, Bukhara Branch, Uzbekistan

Abstract

This research aimed to study the nature of pathomorphological changes in the kidney in chronic alcoholism in rats. In the present study, we have studied experimentally the nature of pathomorphological changes in the kidneys in chronic alcoholism in rats. The longer the intoxication is, the more the kidneys are damaged and homeostatic shifts are more pronounced in young animals. In an experiment on rats, it was found that taking ethanol orally has a short-term effect on kidney tissue and affects water-salt metabolism. Histologically, there are foci of acute inflammation of nephrocytes, spasm of small arterioles, and on the 15th day, atrophic changes in the renal parenchyma. Long-term alcohol intoxication (AIM) leads to persistent morphological disorders of the nephron, which are manifested in changes in the shape and size of the glomerulus, partial sclerosis of loops, vacuolar dystrophy of endothelial cells and partial vacuolar dystrophy of the tubular epithelium, especially the distal part.

Keywords

Chronic Alcoholism,, Rats, Kidney

References

Avdeeva T.G. (1994). The influence of mother's alcoholism on the state of health of the newborn. Paediatrics. P. 57-58.

Anokhina, I. P., Vertinskaia, A. G., Vekshina, N. L., Nebarakova, T. P., Ovchinnikov, I. V., Druzhina, E. V., & Ovchinnikova, O. I. (1999). Hereditary alcoholism: some neurochemical and genetic mechanisms. Vestnik Rossiiskoi akademii meditsinskikh nauk, (6), 43-47.

Apanova O.I., Shelekhin A.A. (2003). Community-acquired pneumonia with the addition of nosocomial infection in persons with chronic alcohol intoxication. News of Science and Technology, Med. Issue Alcoholic disease. P.1-3.

Anokhina, I. P., Vekshina, N. L., & Veretinskaia, A. G. (1997). Central mechanisms of predisposition to psychoactive substance dependence. Zhurnal nevrologii i psikhiatrii imeni SS Korsakova, 97(12), 83-84.

E.N. Akhmadeeva, E.K. Alekhin, N.R. Khusamova (1996). Fetal alcohol syndrome. Healthcare of Bashkortostan. No. 2-3. pp.46-51.

Abdrashidov A.Kh. (1984). Ethanol consumption by rats under conditions of free choice and when giving ethanol solutions as the only source of liquid. Biological bases of alcoholism. Medicine, P. 197-199.

Balika Yu.D., Kartashova V.E., Skosyreva A.M. (1982). The impact of alcohol intoxication of pregnant rats on the hematopoietic system of their offspring. Obstetrics and gynecology. №. 9. P. 56-57.

Ganapolsky V.P. (2003). The system of opioids and stress hormones in severe mechanical trauma and ethanol intoxication. Diss. Cand. Honey. Sciences. SPb, P. 108.

Kazarnovskaya M.JI, Vasilos A.F, Dmitrienko V.D. (1976). Mutagenic effect of ethyl alcohol on human cell culture. 1st All-Union. Congress of forensic doctors. Abstracts. Report Kyiv, P. 594-595.

Kampov-Polevoy A.B, Zhukov V.N. (1979). Study of the baseline alcohol requirement in a laboratory rat population. Dep. IN VINITA. №. 82779.

Beatty M. (1997). Alcoholic in the family or overcoming addiction. Per. from English. P. - 331.

Voloshin V.M. (2002). State prospects of development of children's psychiatric service in Russia. Social and Clinical Psychiatry,T. 12. Issue. 2.- P.5-9.

Garmash I.V., Ryabova A.V., Ezhova L.G. (2003). Severe pneumonia in a patient with alcoholic liver cirrhosis, cytopenia, and disseminated intravascular coagulation (possibilities of modern therapy). News of Science and Technology. Honey series. Issue Alcoholic disease .VINITI, №. 6. P.1-3.

V.A. Guryeva, T.B. Dmitrieva, E.V. Makushkin, V. Ya. Gindikin. (2007). Clinical and forensic adolescent psychiatry. Medical Information Agency,P. 488.

Emelyantseva TA (2000). The role of a family with alcoholic problems in forming deviant behavior in adolescents. Works of young scientists. - Minsk, P. 142-144.

Emelyantseva T.A. (2001). Results and perspectives of psychotherapeutic work on primary prevention of alcohol and drug addiction among adolescents. Minsk, P.210-217.

Mirakyan L.A. (1988). Morphological studies of the mucous membrane of the upper respiratory tract in chronic alcohol intoxication in an experiment on animals. Zh. Ear, nose, throat diseases. №. 3. From 28-30.

Moiseev B.C. (1996). Markers of alcoholic illness. New honey. jou. №. 4. - P. 24-27.

Naydenova N.G. Gordeev M.N. (2002). Alcoholism and pathology of the respiratory system. Narcology, P.23-26.

Nalichko NN (1990). Aspiration pneumonia against the background of alcoholism. Clinical. Medicine. №. 4.P.85-87.

Hovers L.Ya., Ovchinnikov Yu.M., Drozdov E.D., Kudryashova N.D. (1986). The state of ENT organs in patients with chronic alcoholism. Vestnik Otoloroningologii. №. 3.P.71-73.

Arnold, R., Avants, S. K., Margolin, A., & Marcotte, D. (2002). Patient attitudes concerning the inclusion of spirituality into addiction treatment. Journal of substance abuse treatment, 23(4), 319-326.

Burke, R. J., Burgess, Z., & Oberklaid, F. (2003). Workaholism and divorce among Australian psychologists. Psychological reports, 93(1), 91-92.

Christodoulou, G. N., Margariti, M., Kontaxakis, V. P., & Christodoulou, N. G. (2009). The delusional misidentification syndromes: strange, fascinating, and instructive. Current psychiatry reports, 11(3), 185-189.

Coleman-Kennedy, C., & Pendley, A. (2002). Assessment and diagnosis of sexual addiction. Journal of the American Psychiatric Nurses Association, 8(5), 143-151.

Article Statistics

Copyright License

Download Citations

How to Cite

Hamrayev Izzat Sayfullaevich. (2021). Morphological Characteristics Of The Kidney In Chronic Alcoholism. The American Journal of Medical Sciences and Pharmaceutical Research, 3(09), 38–42. https://doi.org/10.37547/TAJMSPR/Volume03Issue09-08