★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★Open research. Global perspectives.
The American Journal of Applied Sciences

Volume 8.
Issue 2.

Volume 08 Issue 02

February 2026

Explore the research published in this issue. Read article details, abstracts and available full-text files.

Open access ISSN 2689-0992 19 articles
tajas ISSN 2689-0992

Ideas without
boundaries.

The American Journal of Applied Sciences

VOLUME 8 / ISSUE 2 FEBRUARY 2026
IN THIS ISSUE

Table of contents.

19 articles

Applied Sciences

19 articles
1
Applied Sciences · OPEN ACCESS 28 February 2026

The Role of the USA, China, And Russia In the Formation of a New World Order

Ajieva Bekzoda Azatovna, Mukhtar Nazirov

Read Abstract

This article examines the evolution and current state of Russia-China relations over the past two decades. Despite repeated attempts to accelerate cooperation, both countries have experienced steady, incremental progress in economic, military, and political spheres. Initially underestimated or dismissed by Western analysts, the partnership has grown into a significant strategic alliance, characterized by mutual economic dependence and coordinated international positions. The analysis highlights the asymmetries in their relationship, emphasizing that Russia’s influence over China remains limited, especially in economic and political terms. The article concludes that Russian-Chinese relations are complex, resilient, and cannot be reduced to simplistic narratives of dominance or subordination.

Read Article PDF
2
Applied Sciences · OPEN ACCESS 28 February 2026

Quantum Natural Language Processing for Next-Generation Intent Recognition: Foundations, Techniques, And Future Directions

Rohan Salvi

Read Abstract

AI-based systems in virtual assistants, conversation agents, and automated platforms rely heavily on intent recognition in Natural Language Processing (NLP). Using TF-IDF with classic classifiers results in reliable baselines, although using major transformer models, such as BERT, offers a deeper analysis and requires many resources. New developments in Quantum Machine Learning (QML) suggest new architectures that might help solve language problems. This study examined different types of intent classification models. A model can be set up using (i) classical TF-IDF + Logistic Regression, (ii) transformer-based BERT, and (iii) a quantum-classical variational quantum circuit (VQC) model from PennyLane. The models were evaluated using a custom JSON dataset with many intent examples. The results indicate that the classical model achieved the best performance among all, generating an accuracy of 68.97% and an F1-score of 70.69%, compared to the performance of BERT (accuracy=65.52% and F1-score = 63.91%) and the VQC model (accuracy=31.03% and F1-score = 25.65%). In addition to explaining the differences in the performance of the models, the visualizations pointed out their sensitive reactions to the structure and level of data in the categories. This paper discusses the advantages and disadvantages of different models, the challenges of using current quantum simulation tools, and the usefulness of QNLP in real-time and privacy-sensitive applications. At this current step in quantum model building, the findings here provide important guidance for future efforts on explainable, scalable, and hardware-accelerated QNLP.

Read Article PDF
3
Applied Sciences · OPEN ACCESS 28 February 2026

Millet Crop Residues for Economical Bioenergy and Chemical Applications

Dr. Tane Williams

Read Abstract

Millet crop residues, an abundant and underutilized agricultural byproduct, present a significant opportunity for sustainable bioenergy and chemical production. This research investigates the potential of millet waste as a feedstock for biofuel and value-added chemical synthesis, emphasizing cost-effectiveness, environmental sustainability, and integration within the circular bioeconomy. The study critically evaluates the current decision-support frameworks and computational modeling tools used in bioenergy system design, including multi-criteria assessment models, ontology-based pathways, and simulation software applications, to optimize conversion processes and yield efficiency. Using a systematic review of literature and case-based computational analyses, the study highlights pathways for converting millet residues into bioethanol, biogas, and other bio-based chemicals, while minimizing environmental footprints and improving energy security. Comparative analyses reveal gaps in existing bioenergy modeling frameworks, particularly in relation to region-specific feedstock variability and techno-economic feasibility. Empirical evidence indicates that millet residues can achieve high conversion efficiencies under optimized processing conditions, providing a renewable energy source with low greenhouse gas emissions. Furthermore, this research identifies the limitations of conventional bioenergy systems, such as process scalability, feedstock pretreatment requirements, and integration with existing agricultural supply chains. The findings underscore the importance of adopting circular economy principles, integrating decision-support tools, and applying simulation-based design approaches to achieve sustainable and economically viable bioenergy production from millet residues. The study concludes that millet crop residues represent a practical, low-cost, and environmentally sound feedstock for bioenergy and chemical applications, with significant potential to contribute to national and global renewable energy targets, while simultaneously supporting rural economies and reducing agricultural waste. Future research should focus on developing region-specific processing models, life-cycle assessments, and techno-economic optimization to fully realize the potential of millet residue-based bioenergy systems (Deshwal & Singh, 2025).

Read Article PDF
4
Applied Sciences · OPEN ACCESS 11 February 2026

Tiktok Vs Instagram: Youth Platform Preferences and PR Strategy Implications

Polina Verdieva

Read Abstract

The study is aimed at identifying and analyzing key determinants that influence the propensity of youth to prefer one social network over another. The methodological basis of the work consisted of a comprehensive systems analysis and synthesis of scholarly publications combined with the processing of statistical datasets from recognized industry sources. As a result, a close relationship was established between user choices and three interrelated factors: the specifics of algorithmic content ranking mechanisms, the dominant formats of materials and the sociocultural constitution features of each network’s community. Thus, TikTok emerges as an ecosystem stimulating authentic self-expression, interactive engagement and the consumption of predominantly entertainment media products, whereas Instagram retains the status of a gallery of visually refined idealized content serving as a means of social validation and personal brand maintenance. The scientific novelty of the study lies in the proposal of an adaptive model of PR strategies that accounts for the unique psychographic and behavioral characteristics of each platform’s users. The findings demonstrate the impossibility of effectively applying universal communication solutions and justify the need to design targeted tactics customized to the specifics of TikTok’s and Instagram’s functioning. The presented materials will be useful to both media communications researchers and PR and marketing practitioners seeking to optimize interactions with youth audiences.

Read Article pdf
5
Applied Sciences · OPEN ACCESS 28 February 2026

Integrative Evaluation of Pomegranate Peel-Derived Bioactive Compounds and Nanoparticles in Zebrafish (Danio Rerio): Implications for Immunomodulation, Antimicrobial Activity, And Neurobehavioral Health

Evan R. Callister

Read Abstract

The increasing demand for sustainable, biologically effective therapeutic agents has intensified research into plant-derived compounds and their integration with advanced nanotechnological systems. Among these, pomegranate peel extract (Punica granatum) has emerged as a potent source of polyphenols with demonstrated antioxidant, antimicrobial, and anti-inflammatory properties. Concurrently, zebrafish (Danio rerio) has gained prominence as a versatile vertebrate model for studying disease mechanisms, pharmacological responses, and toxicological effects. This study synthesizes existing literature to construct a comprehensive, theoretically grounded investigation into the combined application of pomegranate peel-derived bioactive compounds and nanoparticle systems in zebrafish models. Emphasis is placed on immunological responses, antimicrobial efficacy, and neurobehavioral outcomes.

Drawing from interdisciplinary references, the study explores how phytochemical constituents such as ellagic acid and tannins interact with biological systems, both independently and when incorporated into nanoscale delivery platforms. The zebrafish model is critically analyzed for its suitability in evaluating immune modulation, pathogen-host interactions, and neurological changes. Furthermore, the integration of green-synthesized nanoparticles is discussed in relation to enhanced bioavailability and targeted therapeutic action.

The findings suggest that pomegranate peel extract, particularly when utilized in nanoparticle formulations, significantly enhances innate immune responses, reduces microbial proliferation, and influences neurobehavioral parameters in zebrafish. The study also highlights potential mechanistic pathways, including modulation of type I interferon responses and inhibition of enzymatic browning processes. Limitations related to translational applicability and nanoparticle toxicity are addressed, alongside recommendations for future research. Overall, this work contributes a detailed theoretical framework for advancing phytochemical-nanotechnology integration in biomedical research.

Read Article PDF
6
Applied Sciences · OPEN ACCESS 07 February 2026

Improving The Inventory Management Mechanism In Auto Service Enterprises

Abullaev Shuxrat Shapievich

Read Abstract

In the contemporary automotive service industry, inventory management has emerged as one of the most critical determinants of operational efficiency, service quality, and financial sustainability. Auto service enterprises operate in an environment characterized by high demand uncertainty, extensive spare-parts assortment, rapid technological change, and intense competitive pressure. Consequently, traditional inventory management approaches are often insufficient to meet modern requirements. This article provides a comprehensive and deeply analyzed examination of inventory management mechanisms in auto service enterprises and proposes systematic directions for their improvement. Using analytical, comparative, and systemic research methods, the study explores organizational, technological, economic, and human-factor dimensions of inventory management. Practical examples illustrate the real-world applicability of the proposed mechanisms. The findings demonstrate that integrated inventory management—based on analytical tools, digital technologies, risk management, and customer-oriented strategies—significantly enhances inventory turnover, reduces costs, and improves service reliability.

Read Article PDF
7
Applied Sciences · OPEN ACCESS 28 February 2026

Advanced Surface-Enhanced Raman Spectroscopy and Nanobiosensor Technologies For Ultra-Sensitive Detection of Chemical Contaminants in Food Systems

Ananya R. Mehta

Read Abstract

The increasing prevalence of chemical contaminants in food systems, including heavy metals and pesticide residues, necessitates the development of highly sensitive, rapid, and reliable detection technologies. This research article provides a comprehensive and integrative analysis of advanced nanotechnology-driven sensing systems, with a primary focus on surface-enhanced Raman spectroscopy (SERS) and nanobiosensor platforms. Drawing exclusively from the provided references, the study evaluates the theoretical foundations, material innovations, detection mechanisms, and practical applications of nanosensors in food safety. The methodology employs a qualitative synthesis of interdisciplinary research encompassing nanomaterials, spectroscopy, biosensing, and green analytical chemistry. The findings reveal that SERS-based detection systems, particularly those utilizing hybrid nanostructures such as Au@AgPt nanoparticles, graphene composites, and nanorod arrays, demonstrate exceptional sensitivity and selectivity for detecting trace levels of heavy metals and pesticide residues. Additionally, emerging nanomaterials such as MXenes and organic chemical nanosensors offer novel pathways for enhanced signal transduction and multifunctional sensing. The integration of nanobiosensors with environmentally sustainable sample preparation techniques further enhances analytical efficiency while reducing ecological impact. However, challenges related to reproducibility, standardization, and real-world implementation remain significant. The discussion explores the broader implications of these technologies for food safety, regulatory frameworks, and public health, emphasizing the need for interdisciplinary collaboration and innovation. The study concludes that the convergence of SERS technology, nanobiosensing, and green analytical approaches represents a transformative paradigm for ensuring food safety in complex and globalized food systems.

Read Article PDF
8
Applied Sciences · OPEN ACCESS 07 February 2026

Correlating Carbon Emissions with Extreme Weather Events: A Global Data Analysis

Advait Shankar Kambam, Mohit Singh Rana

Read Abstract

Rapid developments in industrialization have significantly induced carbon emissions and consequently aggravated climate change. Distinct correlations between increasing levels of carbon emissions and extreme weather events through anthropogenic activities can provide clear evidence of vulnerabilities. The present study provides a detailed global data analysis that quantitatively links historical human-induced carbon emissions to observed trends in extreme weather phenomena. By synthesizing datasets, a solid statistical and physical connection between emissions and their climatic consequences is established. The analysis reveals that since 1960, fossil fuel emissions have quadrupled, peaking at 10.1 ± 0.5 GtC yr⁻¹ in 2023. This surge has pushed atmospheric CO₂ concentrations beyond 429 ppm, 50% more than the pre-industrial era and a peak not seen in at least 800,000 years. This atmospheric forcing has led to unprecedented global temperatures, with 2024 recorded as 1.55 ± 0.13 °C above the 1850–1900 baseline. While planetary sinks absorb about half of all human-caused emissions, with the ocean sink taking in 2.9 ± 0.4 GtC yr⁻¹ at the expense of ocean acidification, the atmospheric growth rate of CO₂ remains alarmingly high. The definitive link to extreme weather is confirmed through attribution science, which shows that human-caused climate change made 74% of over 600 analyzed extreme events more probable or severe, with some events being "virtually impossible" otherwise. These results offer unequivocal, data-supported evidence that rising carbon emissions are a direct driver of the increased frequency and intensity of devastating heatwaves, floods, and droughts, highlighting the urgent need to accelerate the global shift to a net-zero economy.

Read Article PDF
9
Applied Sciences · OPEN ACCESS 28 February 2026

Synergizing Edge Intelligence and Digital Twin Architectures for Next-Generation 6G Wireless Ecosystems: A Comprehensive Analysis of Technical Requirements, Standardization, And Propagation Modeling

Arjun Sahu

Read Abstract

The evolution of wireless communication is currently at a critical juncture, transitioning from the established paradigms of 5G to the ambitious, ultra-high-frequency landscapes of 6G and beyond. This research article explores the convergence of three pivotal technologies: sub-terahertz (THz) communications, Digital Twin (DT) networks, and Edge Intelligence. By synthesizing existing literature and theoretical frameworks, this paper investigates how the integration of real-time physical-to-digital synchronization can mitigate the inherent propagation challenges of frequencies above 100 GHz. We provide an exhaustive analysis of the architectural requirements for DT-enabled 6G systems, focusing on the role of multi-sensor data fusion and ray-tracing propagation modeling in creating high-fidelity virtual replicas of the radio environment. Furthermore, the study delves into the necessity of Edge and Fog computing to handle the massive computational overhead required for low-latency synchronization. A significant portion of this work is dedicated to the standardization of cross-domain interfaces and secure edge intelligence, ensuring that DT deployments are resilient against adversarial interference. The findings suggest that while the hardware requirements for 6G are daunting, the systemic integration of digital twins and edge-based analytics provides a viable pathway for achieving the terabit-per-second speeds and microsecond latencies envisioned for the next decade.

Read Article PDF
10
Applied Sciences · OPEN ACCESS 01 February 2026

Navigating Perceived Risk, Influencer Credibility, and Emotional Engagement in Social Media Advertising: An Integrated Consumer Response Framework for the Digital Generation

Leonardo F. Vitale

Read Abstract

The rapid expansion of social media platforms has fundamentally transformed how brands communicate with consumers, shifting traditional one-way advertising into interactive, data-driven, and socially embedded marketing ecosystems. This transformation has been accompanied by rising concerns over perceived risk, trust, privacy, manipulation, and authenticity, particularly among younger digital-native audiences. Drawing exclusively from established scholarship on perceived risk, consumer socialization, social media advertising, influencer marketing, emotional appeal, personalization, and platform-specific engagement, this study develops an integrated and theoretically grounded framework to explain how contemporary consumers—especially Generation Z—interpret, evaluate, and respond to social media advertising.

Grounded in the perceived risk model of Dowling and Staelin, this article argues that digital advertising is no longer evaluated only on economic or performance uncertainty, but also on psychological, social, and identity-related risks, especially when mediated by influencers, algorithmic personalization, and peer-generated content. The increasing visibility of influencer marketing and short-form video platforms has introduced new mechanisms of trust and persuasion, in which users rely more heavily on symbolic cues such as relatability, authenticity, follower metrics, and emotional resonance than on formal brand information.

By synthesizing insights from studies on influencer credibility, emotional appeal, informativeness, personalization, and platform-specific content, the article demonstrates that consumer responses to social media advertising are shaped by the interaction between perceived risk and perceived value. While influencer endorsements and emotionally rich content can reduce uncertainty and increase message acceptance, they can also trigger skepticism when users perceive commercial manipulation or identity misalignment. This tension is especially salient among Generation Z, whose high social media engagement and content exposure make them simultaneously more informed and more vulnerable to persuasive messaging.

Using a qualitative analytical framework inspired by Miles and Huberman’s approach to interpretive data synthesis, this research integrates prior empirical findings into a coherent model of consumer decision-making in digital advertising environments. The results show that positive consumer responses are most likely when advertising messages balance emotional engagement, informational transparency, and credible social proof. Conversely, when influencer content or targeted advertising is perceived as intrusive, misleading, or overly commercialized, users engage in defensive risk-handling strategies such as ad avoidance, skepticism, or negative brand evaluation.

This article contributes to digital marketing theory by unifying perceived risk, social influence, and platform-mediated engagement into a single explanatory structure. It also offers strategic implications for brands seeking to communicate effectively with socially connected and psychologically complex digital consumers. By focusing on trust, authenticity, and emotional relevance rather than mere exposure or algorithmic reach, marketers can build more sustainable and ethically grounded relationships with contemporary audiences.

Read Article pdf
11
Applied Sciences · OPEN ACCESS 28 February 2026

Environmental Transformations and Population Health: Effects of Weather Instability on Global Financial Advancement

Dr. Muhammad Khan

Read Abstract

This study examines the interlinked relationship between environmental transformations, population health outcomes, and global financial advancement under conditions of increasing weather instability. It conceptualizes climate variability as a systemic force that reshapes socio-economic development through interconnected ecological, technological, and financial pathways. The research integrates environmental risk frameworks, digital transformation perspectives, and machine learning-based analytical approaches to understand how weather instability influences macroeconomic performance and financial system resilience.

The methodology is based on a structured qualitative synthesis of interdisciplinary literature, including environmental policy frameworks, digital transformation strategies, sustainability studies, and machine learning applications in economic systems. The study evaluates how extreme weather events and long-term climatic instability disrupt population health systems, reduce productivity, and alter financial growth trajectories. It further explores how technological advancements and digital governance frameworks can mitigate or amplify these effects.

Findings indicate that weather instability significantly undermines population health by increasing exposure to extreme environmental conditions, thereby reducing labor productivity and increasing healthcare burdens. These health impacts translate into measurable economic slowdowns and reduced financial market efficiency. Additionally, digital transformation and ICT-based sustainability frameworks demonstrate partial mitigation capacity by improving resource allocation and system responsiveness. However, their effectiveness is constrained by structural environmental risks and policy implementation gaps.

The study also highlights that financial advancement is increasingly dependent on environmental stability, as extreme heat and ecological disruptions pose systemic risks to economic infrastructure and productivity systems. Dwivedi et al. (2025) reinforce this perspective by demonstrating that climate-induced environmental changes significantly influence global economic growth through health-related and productivity channels.

Overall, the research concludes that environmental transformations are not external shocks but central determinants of financial system performance. Sustainable financial advancement requires integrated policy frameworks that address environmental resilience, population health protection, and digital transformation simultaneously.

Read Article PDF
12
Applied Sciences · OPEN ACCESS 28 February 2026

Transition Toward Regenerative Resource Models in Agro-Food Supply Networks

Dr. P. Wang

Read Abstract

The agro-food sector is increasingly challenged by resource depletion, environmental degradation, and systemic inefficiencies embedded within conventional linear supply chain models. These models, characterized by extract-produce-consume-dispose patterns, have intensified ecological pressures and undermined long-term sustainability. In response, regenerative resource models have emerged as a transformative paradigm aimed at restoring ecological balance, optimizing resource cycles, and enhancing system resilience. This study critically examines the transition toward regenerative resource models in agro-food supply networks, integrating perspectives from circular economy theory, supply chain risk management, and energy system optimization.

The research employs a conceptual and analytical synthesis of existing literature to develop a comprehensive framework for regenerative agro-food systems. It explores the interplay between resource circularity, supply chain resilience, and technological innovation, with particular emphasis on energy integration through microgrid systems and advanced optimization techniques. The study further investigates the role of supply chain design under uncertainty, highlighting the importance of robust network configurations in mitigating disruptions and ensuring sustainability.

Findings suggest that regenerative models significantly improve resource efficiency by enabling closed-loop material flows, reducing waste, and enhancing energy self-sufficiency. The integration of microgrid-based energy systems and decentralized resource management mechanisms is identified as a key enabler of regenerative supply networks. However, the transition is constrained by economic, technological, and institutional barriers, including high implementation costs, complexity of system integration, and lack of coordinated policy frameworks.

The study concludes that regenerative resource models represent a viable pathway for transforming agro-food supply networks into sustainable and resilient systems. It emphasizes the need for interdisciplinary approaches, combining economic, technological, and environmental strategies to facilitate large-scale adoption. The research contributes to the academic discourse by providing a structured framework for understanding the dynamics of regenerative systems and their implications for future agro-food sustainability.

Read Article PDF
13
Applied Sciences · OPEN ACCESS 10 February 2026

Chemical-Mineralogical Selection Criteria For Serpentinite-Based Forsterite Refractories

Kadyrova Zulayho Raimovna, Niyazova Shokhista Mansuraliyevna, Kodirova Umida Aslonovna, Kazakova Munira Narzikulovna, Kholmurodova Sokhiba Almakhmat kizi

Read Abstract

The study examines the chemical-mineralogical composition and phase transformations of serpentinites from the Arvaten and Sultan-Uvays deposits to assess their suitability as local raw materials for forsterite refractories. XRD, SEM and chemical analysis were employed. The main stages of thermal transformations and their relationship to the formation of forsterite-bearing phases were identified. The magnesia-silicate and magnesia-iron modules were considered as suitability criteria. The results show that serpentinites from the Arvaten deposit are a promising feedstock for producing forsterite refractory materials.

Read Article PDF
14
Applied Sciences · OPEN ACCESS 28 February 2026

Institutionalization Patterns for Regenerative Closed-Loop Resource Cycling Systems Within Farm Production Nutrition Domains

Javier Gómez

Read Abstract

The institutionalization of regenerative closed-loop resource cycling systems within farm production nutrition domains represents a transformative shift from linear agricultural paradigms toward integrated, feedback-driven resource governance structures. This paper examines how institutional frameworks, standards-based system design principles, and computational modeling approaches collectively shape the adoption and stabilization of circular agro-nutrition ecosystems. The study conceptualizes farm production systems as socio-technical infrastructures governed by procedural standards, regulatory lifecycle models, and knowledge-driven optimization mechanisms.

The methodological approach is grounded in structured systems synthesis, combining institutional analysis with computational systems engineering frameworks derived from ISO/IEC lifecycle standards, IEEE design governance protocols, and model-based optimization theories. Agroecosystem resource cycling is interpreted through closed-loop system representations, where nutrient flows, production outputs, and waste recovery mechanisms are treated as formally governed system entities.

Findings indicate that institutionalization occurs through three dominant pathways: standard-driven system formalization, computational abstraction of agro-nutrition processes, and knowledge-based adaptive governance. Standards such as ISO/IEC 15288 and ISO/IEC 12207 provide lifecycle governance structures that align with regenerative system deployment. IEEE modeling frameworks (IEEE 1320.1, IEEE 1028) enable functional decomposition of agro-nutrition subsystems into verifiable and auditable components. Additionally, domain knowledge integration strategies (Zschaler & Mandow, 2016; Meditskos et al., 2016) enhance adaptive decision-making in resource cycling systems.

The study further identifies that institutionalization effectiveness depends on interoperability between technical standards and ecological processes, as well as the ability to encode agricultural variability into computationally manageable structures. However, challenges remain in aligning biological unpredictability with rigid system engineering frameworks. The research concludes that institutional embedding of regenerative closed-loop systems requires hybrid governance models that integrate engineering rigor with ecological adaptability, supported by circular economy principles (Agarwal et al., 2025).

Read Article PDF
15
Applied Sciences · OPEN ACCESS 07 February 2026

Ten-Year Retrospective Study of Gastric and Gastroesophageal Cancers in South-East Nigeria: Insights into Demographics and Tumour Characteristics

Kenechi Gerald Ike, Chinedu Ndukwe, Badmos Kabir, Kennedy Oberhiri Obohwemu, Celestine Emeka Ekwuluo, Christabel A. Ovesuor, Oladipo Vincent Akinmade, Mary Oluwayemisi Akadiri, Oluwafemi Emmanuel Ooju, Ulunma Ikwuoma Mariere, Jennifer Adaeze Chukwu, Japhet Haruna Jonah, Abba Sadiq Usman, Solomon Atuman, Festus Ituah, Barth Onyekachi Nwokedi, Jerry Soni, Leonard Nnamdi Meruo, Sadi Joel, Nwora Chinonso Oli, Obioma Chidumaga Aririsukwu

Read Abstract

Background: Gastric and gastro‑oesophageal junction cancers remain major contributors to global cancer mortality. In Nigeria, late diagnosis is common, and this pattern continues to drive high cancer‑related deaths.

Materials and Methods: Clinico‑pathological data were retrieved from four major histopathology laboratories in Anambra State, southeast Nigeria. Statistical analysis was conducted using the Chi‑square test in SPSS version 25 to assess differences in proportions.

Results: Gastric and gastro‑oesophageal junction cancers were most frequently diagnosed in individuals in their sixth and seventh decades of life, with a median age of 56.7 years. There was no clear sex predilection in the study population. The pylorus and antrum were the most common tumour locations, and intestinal‑type adenocarcinoma was the predominant histological subtype. Most cases presented at advanced stages, with the majority staged as T3 or T4.

Conclusion: Gastric and gastro‑oesophageal junction cancers in this setting are characterised by late presentation and are predominantly antral adenocarcinomas. These findings highlight the need for a regional screening initiative aimed at earlier detection and improved outcomes.

Read Article PDF
16
Applied Sciences · OPEN ACCESS 28 February 2026

Medicinal Efficacy of Punica Granatum Pericarp Derivatives in A Small Teleost Model: Combined Botanical and Behavioral Evaluation

Aarav Sharma

Read Abstract

The exploration of plant-derived bioactive compounds has gained substantial momentum in contemporary biomedical research due to their therapeutic potential, cost-effectiveness, and reduced adverse effects. Among these, Punica granatum (pomegranate) has emerged as a significant source of phytochemicals, particularly within its pericarp, which is often considered an agro-industrial byproduct. This study investigates the medicinal efficacy of Punica granatum pericarp derivatives using a small teleost model, focusing on an integrative evaluation of phytochemical composition and neurobehavioral outcomes. The research addresses the growing need for alternative therapeutic agents derived from natural products and evaluates their biological activity within a controlled experimental framework.

The study employs a multidisciplinary methodology combining phytochemical profiling, behavioral assays, and functional analysis. Phytochemical constituents such as polyphenols, flavonoids, tannins, and alkaloids are examined for their pharmacological relevance. Behavioral assessments in the teleost model are used to evaluate neuroprotective, anxiolytic, and cognitive-enhancing effects. The integration of botanical analysis with behavioral science enables a comprehensive understanding of the bioactivity of pericarp derivatives.

Findings indicate that Punica granatum pericarp extracts demonstrate significant bioactivity, including antioxidant, antimicrobial, and neurobehavioral modulation effects. These findings are consistent with prior research highlighting the therapeutic potential of pomegranate peel extract in zebrafish models (Agarwal and Usharani, 2026). The study further identifies mechanistic pathways through which these compounds exert their effects, including oxidative stress reduction and modulation of neurotransmitter systems.

The results contribute to the expanding body of knowledge on plant-based therapeutics and support the potential application of Punica granatum derivatives in pharmaceutical and nutraceutical domains. Limitations include variability in phytochemical composition and challenges in translating findings to human systems. Future research should focus on clinical validation and advanced molecular investigations.

Read Article PDF
17
Applied Sciences · OPEN ACCESS 05 February 2026

An Effective Machine Failure Diagnosis Model Using Artificial Intelligence Algorithms

Yaqoob Fadhil Hussein

Read Abstract

This study examines the feasibility of machine failure detection using deep learning approaches in a bid to improve predictive maintenance approaches. A deep-learning model has been created using the AI4I 2020 Predictive Maintenance dataset in order to effectively predict equipment failures. The model is built using two deep learning algorithms Long – Short Term Memory (LSTM), and Convolutional Neural Networks (CNNs). The preprocessing of the data that encompasses data cleaning, feature engineering, and normalization is applied to guarantee data quality. The metrics used to evaluate model performance are accuracy, ROC and AUC. Empirical findings show that the proposed LSTM-CNN model has a high predictive accuracy and significantly better results compared to the other traditional Support Vector Machine (SVM) models, especially when it comes to predicting complex patterns and dependence of operational data. In spite of the benefits, there are still issues of data quality, architecture, hyperparameter choice, and model interpretability. In general, the research validates the high potential of deep learning in reliable machine failure detection and specifies the main directions of future studies.

Read Article PDF
18
Applied Sciences · OPEN ACCESS 28 February 2026

Assessment of Slope Indicators for Agricultural Lands with Complex Terrain

Musurmankulova Shaxlo Axmedovna

Read Abstract

This study assesses slope indicators of agricultural lands with complex terrain in the Tashkent region of Uzbekistan using GIS and remote sensing technologies. The Perfect Slope web platform was developed by integrating digital elevation models, Sentinel-2 imagery, precipitation, and land-cover data within the ArcGIS Pro environment. To evaluate the platform's accuracy, field measurements were conducted at 200 geodetic points, including slope observations at 100 locations, and compared with remotely derived data. The results showed a strong correlation between field and remote measurements (r ≥ 0.94), while the maximum slope estimation error did not exceed 1.2°. Statistical evaluation using MSE, RMSE, and R² confirmed high accuracy for gentle slopes and acceptable performance for steeper terrain. The developed platform provides a reliable tool for slope assessment, land suitability analysis, and sustainable agricultural land management in areas with complex relief.

Read Article pdf
19
Applied Sciences · OPEN ACCESS 22 February 2026

Reconfiguring Business Consulting Architectures for Small and Medium-Sized Enterprises through Integrated Business Model Innovation and Networked Strategic Change

Vivienne M. Holloway

Read Abstract

The contemporary environment of small and medium-sized enterprises is characterized by accelerating technological change, intensifying competitive pressures, fragmented markets, and the increasing importance of intangible strategic resources. Within this complex context, business consulting is no longer a peripheral support function but has become a central mechanism through which SMEs can adapt, innovate, and remain viable. Despite the growing importance of consulting, the theoretical and methodological foundations that explain how consulting interventions systematically influence business model innovation, organizational legitimacy, and network-based competitiveness remain fragmented and underdeveloped. This research article develops and elaborates a comprehensive theoretical and methodological framework for business consulting for SMEs by integrating the complex consulting model proposed by Kovalchuk (2025) with established perspectives from business model theory, innovation management, network theory, and corporate social responsibility research.

The study argues that consulting for SMEs cannot be reduced to technical advice or episodic problem solving but should be understood as a multi-layered socio-economic process that reconfigures organizational structures, strategic orientation, and inter-organizational relationships. Drawing on business model literature that emphasizes value creation, value capture, and value delivery as dynamic and interdependent processes, the article demonstrates that consulting interventions can function as catalysts for business model innovation when they are embedded within broader organizational and network contexts (Johnson et al., 2008; Magretta, 2002; Foss and Saebi, 2017). The complex consulting model elaborated by Kovalchuk (2025) is used as a central analytical lens to explain how consulting processes integrate diagnostic, design, implementation, and feedback loops in ways that align strategic intent with operational capability.

Methodologically, this research adopts a qualitative integrative design that synthesizes insights from multiple streams of literature. Rather than presenting statistical testing, the study develops a conceptually rich interpretive analysis that maps how consulting activities interact with business model patterns, network structures, and legitimacy-building mechanisms. This approach allows for a nuanced understanding of how SMEs can use consulting not only to solve immediate problems but also to develop long-term strategic resilience.

The results indicate that effective consulting contributes to SME performance by enabling systematic business model adaptation, strengthening network embeddedness, and enhancing organizational legitimacy in the eyes of stakeholders, including customers, governments, and partners (Saebi et al., 2017; Hu et al., 2020; Wenqi et al., 2022). The discussion further situates these findings within broader debates on innovation, corporate responsibility, and strategic change, highlighting both the opportunities and the structural constraints that shape consulting outcomes.

Overall, this article contributes to theory by integrating the complex consulting model of Kovalchuk (2025) into the mainstream discourse on business model innovation and SME strategy. It also offers a robust conceptual foundation for practitioners and policymakers seeking to design consulting systems that foster sustainable competitiveness in the SME sector.

Read Article PDF