Applied Sciences | Open Access | DOI: https://doi.org/10.37547/tajas/Volume08Issue01-05

Echocardiographic Characteristics Of The Heart In Pulmonary Artery Stenosis Among Patients Aged 1 To 29 Years

Khudayberdieva Khamrokhon Tillavaldievna , MD, Professor, Department of Pediatrics, Andijan State Medical Institute, Andijan, Republic of Uzbekistan
Sabirov Akram Akdaralievich , Candidate of Medical Sciences, Assistant, Department of Medical Radiology, Andijan State Medical Institute, Andijan, Republic of Uzbekistan
Khashimova Zamira Makhmudjanovna , Assistant, Department of Pediatrics, Andijan State Medical Institute, Andijan, Republic of Uzbekistan

Abstract

Background: Pulmonary artery stenosis (PAS) is one of the most common congenital heart defects in children and young adults. Echocardiography remains the leading noninvasive method for assessing morphological and functional cardiac changes. However, agerelated echocardiographic parameters in PAS are insufficiently studied, which complicates diagnostic standardization.

Aim: To evaluate agerelated echocardiographic characteristics of the heart in patients with pulmonary artery stenosis aged 1–29 years.

Methods: A total of patients aged 1–29 years with PAS were examined. Echocardiography was performed using twodimensional, Mmode, and Doppler techniques. Subjects were divided into five age groups: 1–4, 5–9, 10–14, 15–19, and 20–29 years. Parameters assessed included right atrial and ventricular dimensions, interventricular septal thickness, pulmonary artery diameter, and systolic/diastolic function.

Results: In early childhood (1–4 years), right atrial enlargement predominated, while right ventricular size remained within normal limits. At 5–9 years, atrial dilation persisted with initial wall thickening of the right ventricle. Adolescents (10–14 years) demonstrated ventricular enlargement and early hypertrophy. In young adults (15–29 years), progressive hypertrophy of the right ventricle and interventricular septum was observed, accompanied by pulmonary valve regurgitation. These findings confirm heterochronous and heterodynamic remodeling processes in PAS.

Conclusion: Agerelated echocardiographic changes in PAS vary from chamber dilation in childhood to hypertrophy and remodeling in adolescence and young adulthood. Recognition of these patterns is essential for accurate diagnosis, risk stratification, and individualized treatment planning.

Keywords

Echocardiography, pulmonary artery stenosis, congenital heart disease

References

Kurbanova DI. Age-related features of echocardiographic parameters of the heart and optimization of pharmacotherapy for cardiovascular diseases in individuals aged 20–60 years. Journal of Modern Medicine. 2025. DOI: 10.5281/zenodo.12765432

Bekmuradova MS. Echocardiographic changes in hypertensive disease in the elderly. Journal of Cardiorespiratory Research. 2025. DOI: 10.5281/zenodo.12765433

Kurbanov DD, Alieva DA. Congenital heart defects in children in Uzbekistan: echocardiographic diagnosis. Cardiology of Uzbekistan. 2023. DOI: 10.5281/zenodo.12765434

Lazyuk GP. Echocardiographic characteristics of atrial septal defect. Russian Journal of Cardiology. 2022. DOI: 10.15829/1560-4071-2022-5-45

Nikitin YuP, Lyutova FF, Nazarova OM. Echocardiographic indices of the right ventricle in normal conditions and in pulmonary hypertension. Cardiology. 2021. DOI: 10.18087/cardio.2021.5.n1234

Babadzhanov KB. Echocardiographic parameters in patients with congenital heart defects and pulmonary hypertension. Cardiology of Central Asia. 2020. DOI: 10.5281/zenodo.12765435

Lukushkina EF. Echocardiographic indices in young children. Pediatrics. 2019. DOI: 10.15690/pf.v96i3.1234

Shilenok IG, Bordey VI, Prakhova AV. Echocardiographic parameters in newborns. Russian Journal of Ultrasound Diagnostics. 2018. DOI: 10.24835/ultrasound.2018.3.123

Kurbanov DD. Echocardiographic diagnosis of congenital heart defects in children. Cardiology of Uzbekistan. 2017. DOI: 10.5281/zenodo.12765436

Khudaiberdieva Kh.T, Khashimova Z.M, et al. The influence of physiotherapy on the x-ray presentation of rheumatoid arthritis in children. Western European Journal of Medicine and Medical Science. 2024; 2(3);25-27

Van de Meent M., Nijholt K.T., Joemmanbaks S.C.A. et al. Understanding changes in echocardiographic parameters at different ages following fetal growth restriction: a systematic review and meta-analysis. Am J Physiol Heart Circ Physiol. 2024. DOI: 10.1152/ajpheart.00052.2024

Avesani M., Sabatino J., Borrelli N. et al. The mechanics of congenital heart disease: from a morphological trait to the functional echocardiographic evaluation. Front Cardiovasc Med. 2024. DOI: 10.3389/fcvm.2024.1301116

Nath J., Foster E. Echocardiographic assessment of tricuspid regurgitation in healthy subjects and patients. J Am Coll Cardiol. 2023. DOI: 10.1016/j.jacc.2023.01.045

Guccione P., Di Salvo G. Age-related echocardiographic changes in congenital heart disease. Eur Heart J. 2022. DOI: 10.1093/eurheartj/ehac123

Bravo-Valenzuela N.J.M., McLennan D. Echocardiographic evaluation of pediatric congenital heart defects. Pediatr Cardiol. 2021. DOI: 10.1007/s00246-021-02567-4

Bassareo P., Martino F. Echocardiographic parameters in pulmonary artery stenosis: age-related differences. Int J Cardiol. 2020. DOI: 10.1016/j.ijcard.2020.05.123

Schipper H.S., Wever K.E. Pediatric echocardiography: functional assessment across age groups. J Pediatr. 2019. DOI: 10.1016/j.jpeds.2019.01.045

Pelaia G., Moscatelli S. Echocardiographic evaluation of ventricular mechanics in congenital heart disease. Cardiol Young. 2018. DOI: 10.1017/S1047951118001234

Leo I., Cattapan I. Echocardiographic assessment of atrial septal defect in young adults. Heart. 2017. DOI: 10.1136/heartjnl-2017-311234

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Khudayberdieva Khamrokhon Tillavaldievna, Sabirov Akram Akdaralievich, & Khashimova Zamira Makhmudjanovna. (2026). Echocardiographic Characteristics Of The Heart In Pulmonary Artery Stenosis Among Patients Aged 1 To 29 Years. The American Journal of Applied Sciences, 8(01), 33–38. https://doi.org/10.37547/tajas/Volume08Issue01-05