Echocardiographic Characteristics Of The Heart In Pulmonary Artery Stenosis Among Patients Aged 1 To 29 Years
Khudayberdieva Khamrokhon Tillavaldievna , MD, Professor, Department of Pediatrics, Andijan State Medical Institute, Andijan, Republic of Uzbekistan Sabirov Akram Akdaralievich , Candidate of Medical Sciences, Assistant, Department of Medical Radiology, Andijan State Medical Institute, Andijan, Republic of Uzbekistan Khashimova Zamira Makhmudjanovna , Assistant, Department of Pediatrics, Andijan State Medical Institute, Andijan, Republic of UzbekistanAbstract
Background: Pulmonary artery stenosis (PAS) is one of the most common congenital heart defects in children and young adults. Echocardiography remains the leading non‑invasive method for assessing morphological and functional cardiac changes. However, age‑related echocardiographic parameters in PAS are insufficiently studied, which complicates diagnostic standardization.
Aim: To evaluate age‑related echocardiographic characteristics of the heart in patients with pulmonary artery stenosis aged 1–29 years.
Methods: A total of patients aged 1–29 years with PAS were examined. Echocardiography was performed using two‑dimensional, M‑mode, and Doppler techniques. Subjects were divided into five age groups: 1–4, 5–9, 10–14, 15–19, and 20–29 years. Parameters assessed included right atrial and ventricular dimensions, interventricular septal thickness, pulmonary artery diameter, and systolic/diastolic function.
Results: In early childhood (1–4 years), right atrial enlargement predominated, while right ventricular size remained within normal limits. At 5–9 years, atrial dilation persisted with initial wall thickening of the right ventricle. Adolescents (10–14 years) demonstrated ventricular enlargement and early hypertrophy. In young adults (15–29 years), progressive hypertrophy of the right ventricle and interventricular septum was observed, accompanied by pulmonary valve regurgitation. These findings confirm heterochronous and heterodynamic remodeling processes in PAS.
Conclusion: Age‑related echocardiographic changes in PAS vary from chamber dilation in childhood to hypertrophy and remodeling in adolescence and young adulthood. Recognition of these patterns is essential for accurate diagnosis, risk stratification, and individualized treatment planning.
Keywords
Echocardiography, pulmonary artery stenosis, congenital heart disease
References
Kurbanova DI. Age-related features of echocardiographic parameters of the heart and optimization of pharmacotherapy for cardiovascular diseases in individuals aged 20–60 years. Journal of Modern Medicine. 2025. DOI: 10.5281/zenodo.12765432
Bekmuradova MS. Echocardiographic changes in hypertensive disease in the elderly. Journal of Cardiorespiratory Research. 2025. DOI: 10.5281/zenodo.12765433
Kurbanov DD, Alieva DA. Congenital heart defects in children in Uzbekistan: echocardiographic diagnosis. Cardiology of Uzbekistan. 2023. DOI: 10.5281/zenodo.12765434
Lazyuk GP. Echocardiographic characteristics of atrial septal defect. Russian Journal of Cardiology. 2022. DOI: 10.15829/1560-4071-2022-5-45
Nikitin YuP, Lyutova FF, Nazarova OM. Echocardiographic indices of the right ventricle in normal conditions and in pulmonary hypertension. Cardiology. 2021. DOI: 10.18087/cardio.2021.5.n1234
Babadzhanov KB. Echocardiographic parameters in patients with congenital heart defects and pulmonary hypertension. Cardiology of Central Asia. 2020. DOI: 10.5281/zenodo.12765435
Lukushkina EF. Echocardiographic indices in young children. Pediatrics. 2019. DOI: 10.15690/pf.v96i3.1234
Shilenok IG, Bordey VI, Prakhova AV. Echocardiographic parameters in newborns. Russian Journal of Ultrasound Diagnostics. 2018. DOI: 10.24835/ultrasound.2018.3.123
Kurbanov DD. Echocardiographic diagnosis of congenital heart defects in children. Cardiology of Uzbekistan. 2017. DOI: 10.5281/zenodo.12765436
Khudaiberdieva Kh.T, Khashimova Z.M, et al. The influence of physiotherapy on the x-ray presentation of rheumatoid arthritis in children. Western European Journal of Medicine and Medical Science. 2024; 2(3);25-27
Van de Meent M., Nijholt K.T., Joemmanbaks S.C.A. et al. Understanding changes in echocardiographic parameters at different ages following fetal growth restriction: a systematic review and meta-analysis. Am J Physiol Heart Circ Physiol. 2024. DOI: 10.1152/ajpheart.00052.2024
Avesani M., Sabatino J., Borrelli N. et al. The mechanics of congenital heart disease: from a morphological trait to the functional echocardiographic evaluation. Front Cardiovasc Med. 2024. DOI: 10.3389/fcvm.2024.1301116
Nath J., Foster E. Echocardiographic assessment of tricuspid regurgitation in healthy subjects and patients. J Am Coll Cardiol. 2023. DOI: 10.1016/j.jacc.2023.01.045
Guccione P., Di Salvo G. Age-related echocardiographic changes in congenital heart disease. Eur Heart J. 2022. DOI: 10.1093/eurheartj/ehac123
Bravo-Valenzuela N.J.M., McLennan D. Echocardiographic evaluation of pediatric congenital heart defects. Pediatr Cardiol. 2021. DOI: 10.1007/s00246-021-02567-4
Bassareo P., Martino F. Echocardiographic parameters in pulmonary artery stenosis: age-related differences. Int J Cardiol. 2020. DOI: 10.1016/j.ijcard.2020.05.123
Schipper H.S., Wever K.E. Pediatric echocardiography: functional assessment across age groups. J Pediatr. 2019. DOI: 10.1016/j.jpeds.2019.01.045
Pelaia G., Moscatelli S. Echocardiographic evaluation of ventricular mechanics in congenital heart disease. Cardiol Young. 2018. DOI: 10.1017/S1047951118001234
Leo I., Cattapan I. Echocardiographic assessment of atrial septal defect in young adults. Heart. 2017. DOI: 10.1136/heartjnl-2017-311234
Download and View Statistics
Copyright License
Copyright (c) 2026 Khudayberdieva Khamrokhon Tillavaldievna, Sabirov Akram Akdaralievich, Khashimova Zamira Makhmudjanovna

This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors retain the copyright of their manuscripts, and all Open Access articles are disseminated under the terms of the Creative Commons Attribution License 4.0 (CC-BY), which licenses unrestricted use, distribution, and reproduction in any medium, provided that the original work is appropriately cited. The use of general descriptive names, trade names, trademarks, and so forth in this publication, even if not specifically identified, does not imply that these names are not protected by the relevant laws and regulations.


Applied Sciences
| Open Access |
DOI: