Medical Science
| Open Access |
DOI: Amino Acid Profile of Blood Serum in Normal Conditions and In Myocardial Infarction
Rashidova DurdonaAkhad qizi , PhD, Department of medical and biological chemistry, biophysics and medical informatics, Tashkent State Medical University, Uzbekistan Yuldashev Nosirdjan Muhamedjanovich , Professor, Department of medical and biological chemistry, biophysics and medical informatics, Tashkent State Medical University, Uzbekistan Toshboeva Umida Furkat qizi , Master's degree, Tashkent State Medical University, UzbekistanAbstract
This study focuses on changes in the amino acid composition of blood serum in patients with myocardial infarction. The amino acid profile is considered to reflect the metabolic changes that occur during a heart attack. Analysis of changes in free amino acids in the blood in this category of patients can contribute to a deeper understanding of metabolic disorders in myocardial infarction and expand our understanding of potential targets for metabolic correction.
Keywords
Amino acids, blood serum, nonessential amino acids
References
Yuldashev N., Rashidova D. Experimental evidence of the effectiveness of glycine in myocardial infarction //Contemporary aspects of the development of fundamental sciences and issues of their teaching. – 2023. – Vol. 1. – No. 1. – Pp. 135–143.
Rashidova D. A. Protective properties of glycine in acute hypoxia and adrenal damage in experiments //VolgaMedScience. – 2022. – P. 75-77.
Rashidova D. A. The dependence of myocardial infarction development on the level of free amino acids in blood serum //Infection, immunity, pharmacology. – 2025. – №. 3. – С. 329-333. https://infectionimmunity.uz/media/attachments/2025/05/27/infection-immunity-3- 2025.pdf
Ruiz-Canela M, et al. Plasma amino acids and risk of cardiovascular disease. Circulation. 2020;141(10):803–815.
Wang Q, et al. Metabolomic profiling in acute myocardial infarction patients. Front Cardiovasc Med. 2021;8:645493.
Zhou X, et al. Glutamine metabolism in cardiovascular disease. Biochim Biophys Acta Mol Basis Dis. 2022;1868(3):166321.
Li J, Zhang S, et al. Methionine metabolism and cardiovascular disorders. Nutrients. 2020;12(11):3475.
Perna AF, et al. Sulfur amino acid metabolism in oxidative stress and cardiovascular disease. Int J Mol Sci. 2021;22(7):3672.
Luo X, et al. Serum metabolomics reveals biomarkers of acute myocardial infarction. Metabolites. 2023;13(2):214.
Opie LH. Metabolism of the ischemic myocardium. Heart Physiol. 2020;318(5):H1075–H1084.
Tzoulaki I, et al. Metabolic biomarkers associated with coronary heart disease. Eur Heart J. 2022;43(29):2830–2840.
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Copyright (c) 2026 Rashidova DurdonaAkhad qizi, Yuldashev Nosirdjan Muhamedjanovich, Toshboeva Umida Furkat qizi
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