The Role Of Laboreatory Biomarkers In The Diagnosis Of Early Cartilage Destruction In Reactive Arthritis
Khalmetova F.I. , Tashkent Medical Academy, Uzbekistan Akhmedov K.S. , Tashkent Medical Academy, UzbekistanAbstract
Reactive arthritis is an inflammatory lesion of the joints that occurs as a reaction to the invasion of the body by any infectious agents. The high social significance of nosologies dictates the need to search for reliable cartilage biomarkers that have diagnostic value not only in recognizing degenerative changes at an early stage of joint deseases, but also in monitoring the effectiveness of treatment.
Keywords
Reactive arthritis, biomarker, oligomeric matrix protein of cartilage
References
Starodubtseva I.A., Vasilyeva L.V. Comparative analysis of cartilage oligomere matrix protein in blood serum of the patients with skeletal system diseases // Clinical laboratory diagnosis. 2016. Vol. 61. № 2. p. 83-86. (in Russian)
Carrasco R., Barton A. Biomarkers of outcome in rheumatoid arthritis // Rheumatology Reports.-2010.-Vol. 2 (1). P. 26-38.
Mease P.J. The potential roles for novel biomarkers in rheumatoid arthritis assessment // Clin. Exp. Rheumatol. - 2011. - Vol. 29. - P. 567-574.
Kunder Y.V. Reactive arthritis // Medical news. 2015. №11. p. 8–13. (in Russian)
Khripunova I.G., Jurbina N.V. Reactive arthritis // Guidelines. Stavropol , 2013, pp 3-5. (in Russian)
Alekseyeva Y.I., Jolobova Y.S. Reactive arthritis in children Problems of modern pediatrics, 2013, Vol.2, №1, p. 51-56. (in Russian)
Gniloribov A.M. The role of cartilage oligomere matrix protein in the diagnosis of joint damages // Ukr. Rheum. Jour. 2008. 17 (3). p. 8-11. (in Russian)
Lotz M., Martel-Pelletier J., Christiansen C., BReAndi M.L., Bruyere O., Chapurlat R. et al. Value of biomarkers in osteoarthritis: current status and perspectives. Ann. Rheum. Dis. 2013; 72 (11): 1756-1763.
Starodubtseva I.A., Vasilyeva L.V. Secondary osteoarthrosis in rheumatic arthritis // Clinitcist, 2015, №1, p 24-29. (in Russian)
Marti C., Neidhart M. Cartilage Oligomerix Matrix Protein (COMP): Die Rolle eines nichtkollagenen Knorpel-Matrix-Proteins als Marker der Kran-kenheitsaktivitat und Gelenkzerstorung bei Patienten mit rheumatoi-der Arthritis und Arthrose. Z Rheum. 2016; 58: 79-87.
Tseng S., Reddi A.H., Di Cesare P.E. Cartilage oligomeric matrix protein (COMP): a biomarker of arthritis. Biomark. Insights. 2015; 17 (4): 33-44.
Novikov a.A., Aleksandrova Y.N. Role of cytokines in the pathogenesis of rheumatoid arthritis // scientific-practical rheumatology. 2012. №2, p. 71–82. (in Russian)
Gaponova T.V., Lila A.M. Study of cytokine status in patients with reactive arthritis // Medical Immunology. 2018, Vol. 10, № 2-3, pp. 167-172. (in Russian)
Belgov A.U. Reactive arthritis; diagnosis and therapy // Treatment. 2013. №2. p. 45-52. (in Russian)
Juravleva M.O. assessment of efficacy and tolerance of various courses of azitromicin (sumamed) administration in urogenic reactive arthritis // Archive of internal medicine. Special edition.2014, p.31-35. (in Russian)
Turin V.A. Clinical chaReActeristics and molecular genetic aspects of osteoarthrosis in patients with dysplasia of connective tissue //AbstReAct of dict. Thesis. Moscow. 2015. (in Russian)
Akmayev I.G. Histology guideline. Vol. 1 St. Petersburg, 2014. p 250-251. (in Russian)
Chen, Y. Age at onset of rheumatoid arthritis: association with polymorphisms in the vascular endothelial growth factor A(VEGFA) gene and an intergenic locus between matrix metalloproteinase (MMP) 1 and 3 genes / Y. Chen, D.L. Mattey // Clin. Exp. Rheumatol. - 2015. - Vol. 30, № 6. - P. 894-898.
Nasonov Y.L. Implementation of high medical technologies in rheumatology; problems and solutions // Scientific practical rheumatology. 2008, №2, p.4-5. (in Russian)
Ivanova O.N., Sobolev U.A., Pyadova Y.A. Comparative analysis of arthrosonographic and radiological alterations in joints in rheumatic diseases // Scientific pReActical rheumatology. 2004, №4, p11. (in Russian)
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