Diagnosisand Therapy Of Pancreatic Dysfunction In Atopic Dermatitis In Children
Khalmatova Barnoturdixodjayevna , Professor, Head Of The Department Of Children's Diseases №1, Tashkent Medical Academy, Tashkent, Uzbekistan Mirrakhimova Maktuba Khabibullayevna , Docent,Dsc, Department Of Children's Diseases №1, Tashkent Medical Academy, Tashkent, Uzbekistan Nishonboyeva Nilufar Yunusjanovna , Assistant, First Faculty Of Children’s Diseases, Tashkent Medical Academy, Tashkent, UzbekistanAbstract
Most of allergic diseases are caused by allergic skin lesions.The aim of the study was to assess the effectiveness of the enzyme agents in the correction of pancreatic insufficiency in children with atopic dermatitis.As a result of the study clinical and laboratory markers of relative pancreatic insufficiency were identified in 69.7% of the patients, who required the prescription of enzyme agents. The results also showed that in 92.5% of patients the correction of exocrine function disorders to a certain extent affects the regression of dermal manifestations. In the scatological tests the loss of neutral fat, normalization of the amount of elastase in feces serve to be a marker of the effectiveness of the enzymatic therapy.
Keywords
Atopic dermatitis, children, IgE, pancreatic dysfunction, elastase, diagnosis, treatment
References
AkhrorovK.K. etal. Triggerfactorsofatopicdermatitisinpre-schoolagechildren [Triggerniyefaktoriatopicheskogodermatitaudeteidoshkolnogovozrasta]// Russ.Jour.ofDerm&VenDesiases.2017. Vol. 20. № 6. p. 347-351. (in Russian)
Alekseyeva A.A. Application of enterosorbents in the complex therapy of atopic dermatitis [Primeneniyeenterosorbentovvkomplexsnoiterapiiatopicheskogodermatita] // Problems of modern pediatrics. 2012.Vol.11. № 2.p.151-154. (in Russian)
BalabolkinI.I. Modernnotionsofpathogenesisandtherapyofatopicdermatitisinchildren [Sovremenniyepredstavleniyaopatogenezeiterapiiatopicheskogodermatitaudetei] // Pharmateka. 2017.№1. (334). p. 53-60. (in Russian)
Ibragimova S.A., MirrahimovaM. Kh., Yunusjanovna N.N., Abdullaev B.Sh. Comordid course of atopic dermatitis with bronchial asthma in children: frequency, clinical and allergological characteristics//Journal of Critical Reviews.- Vol.7.- Issue 17. 2020. - P.2317-2321 Scopus (3).
Incidence rates of atopic dermatitis, asthma, and allergic rhinoconjunctivitis in Danish and Swedish children. Henriksen L. et al. // J Allergy ClinImmunol. 2015 Aug; 136(2): 360-6.
KalujhnayaL.D. etal. Characteristics of allergologic status of the patients with atopic dermatitis dependent on family predisposition [Osobennostiallergologicheskogostatusapatsientovbolnihatopicheskimdermatitomvzavisimistiotsemeinoipredraspolojhennosti] // Dermatology and venerology. 2015. № 2 (68). p. 49-60. (in Russian)
Khalmatova B.T, Mirrakhimova M. Kh, IbragimovaSh.A. Immunological changes in the comorbid course of atopic dermatitis. ACADEMICIA: An International Multidisciplinary Research journalhttps://saarj.com Vol. 11, Issue 2, February 2021
Lactobacillus plantarum IS-10506 supplementation reduced SCORAD in children with atopic dermatitis. Prakoeswa CRS. et al. //Benef Microbes. 2017 Oct 13;8(5):833-840.
Lower Prevalence of Atopic Dermatitis and Allergic Sensitization among Children and Adolescents with a Two-Sided Migrant Background.Ernst SA;. Et al. //Int J Environ Res Public Health, 2016 Feb 26; Vol. 13 (3); Publisher: MDPI; PMID: 26927147
M. K. Mirrakhimova et al.: Characteristics of Allergic Pathologies Progression in Young Children. American Journal of Medicine and Medical Sciences 2020, 10(9): 652-656
Mirrahimova M.K., Khalmatova B.T., Ibragimova S.A. Atopic dermatitis and the condition of the intestine in children. Experimental and Clinical Gastroenterology. 2019;(5):126-128. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-165-5-126-128
Mirrakhimova M. X. et al /Antileukotriene Drugs in The Treatment of Atopic Dermatitis in Children. International Journal of Pharmaceutical Research |Jan - Mar 2021|Vol 13 | Issue 1: 2117-2121
Mirrakhimova M.K. Development and implementation into practice of a questionary for detection of allergic diseases prevalence among children [Bolalardaallergikkasalliklarnitarkalishinianiklashmaksadidasurovnomaishlabchikishvauniamaliyotgatadbikkilish] // Biomedicine and practice. Tashkent, 2019. №3.p.41-45. (14.00.00; №24). (in Uzbek)
Mirrakhimova M.K., Nishonboyeva N.U. Atopic dermatitis and digestive organs in children [Atopicheskiidermatitisostoyaniyeorganovpishevareniyaudetei]//Tashkent Medical Academy Bulletin. Tashkent, 2020. №2. p.31-34 (14.00.00; №13). (in Russian)
Muratova J.K. Prevalence of atopic dermatitis among school children living in Jalalabad city according to ISAAC [Rasprostranyonnostatopicheskogodermatitasredishkolnikovprojivayushihvjalalabadepodannimisaak] // KSMA Bulletin. 2016. № 4. p. 16-18. (in Russian)
Nishonboyeva N. Y.,Mirrahimova M. Kh., Ibragimova S.A. Digestive organs status in children with atopic dermatitis //Journal of Critical Reviews. - Vol. 7. - Issue 5. 2020. - P. 678-679. Scopus (3).doi: 10.31838/jcr.07.05.139
Penkina N.I. et al. Atopic dermatitis in children [Atopicheskidermatitudetei] // Health, demography, ecology of finn-ugor nations. 2015. № 4. p. 76-80. (in Russian)
The medical rehabilitation of the children presenting with atopic dermatitis (a literature review). Kotenko KV. et al.//VoprKurortolFizioter Lech FizKult. 2016.- 93(5).-Р.66-70.
ZakirovaUmidaIrkinovna et al /Analysis Of The Prevalence Of Bronchial Asthma In Children In Outpatient Clinics. International Journal of Pharmaceutical Research | Oct - Dec 2020 | Vol 12 | Issue 4: 759-765
Article Statistics
Copyright License
Copyright (c) 2021 The American Journal of Medical Sciences and Pharmaceutical Research
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors retain the copyright of their manuscripts, and all Open Access articles are disseminated under the terms of the Creative Commons Attribution License 4.0 (CC-BY), which licenses unrestricted use, distribution, and reproduction in any medium, provided that the original work is appropriately cited. The use of general descriptive names, trade names, trademarks, and so forth in this publication, even if not specifically identified, does not imply that these names are not protected by the relevant laws and regulations.