Articles
| Open Access | THE ANTIMICROBIAL ACTION OF PETIVERIA ALLIACEA STEM EXTRACT: INVESTIGATING MECHANISMS AND EFFICACY
Astria Santoso , Sekolah Tinggi Farmasi Bandung, Bandung, IndonesiaAbstract
Petiveria alliacea, a plant traditionally used in folk medicine, has shown significant potential for antimicrobial activity. This study investigates the antimicrobial properties and mechanisms of action of the stem extract of Petiveria alliacea against a range of pathogenic microorganisms. The extract was tested against both Gram-positive and Gram-negative bacteria, as well as fungi, using standard microbiological assays. The results demonstrated strong antimicrobial efficacy, with notable inhibition zones against several bacterial and fungal strains. Additionally, the study explores the mechanisms underlying these effects, including the disruption of microbial cell walls, membrane integrity, and enzyme inhibition. These findings suggest that Petiveria alliacea stem extract could serve as a promising natural antimicrobial agent, contributing to the development of alternative therapies for combating infections.
Keywords
Petiveria alliacea, Antimicrobial activity, Stem extract
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