This paper presents a unique case report of concurrent Light Chain Disease (LCD) and Pure Red Cell Aplasia (PRCA), two rare hematological disorders seldom observed together. Light Chain Disease is a plasma cell disorder characterized by the overproduction of abnormal immunoglobulin light chains, while Pure Red Cell Aplasia is a rare bone marrow failure syndrome resulting in the selective reduction or absence of red blood cell precursors. The co-occurrence of these conditions poses diagnostic and therapeutic challenges due to their distinct pathophysiologies and clinical presentations. Through a detailed examination of the patient's medical history, diagnostic workup, and treatment outcomes, this case sheds light on the complexities associated with managing rare hematological disorders with overlapping manifestations.

Light Chain Disease, Pure Red Cell Aplasia, co-occurrence

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