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DOI: OPTIMIZING OXYGENATION: UNVEILING THE POTENTIAL OF INHALED NITRIC OXIDE IN THE MANAGEMENT OF EISENMENGER SYNDROME
Muhammad Triastuti , Department of Pharmacology, Medical Faculty of University Muhammadiyah of Surabaya, Indonesia Anas Airlangga , Department of Cardiology, Medical Faculty of University Muhammadiyah of Surabaya, IndonesiaAbstract
Eisenmenger Syndrome poses a complex challenge in the realm of congenital heart diseases, characterized by pulmonary hypertension and shunting of blood. This paper delves into the potential of inhaled nitric oxide (iNO) as a therapeutic intervention for optimizing oxygenation in individuals with Eisenmenger Syndrome. Through a comprehensive review of existing literature, clinical studies, and case reports, this research explores the physiological mechanisms, safety profile, and efficacy of iNO in ameliorating hypoxemia and pulmonary vascular resistance associated with Eisenmenger Syndrome. The findings aim to contribute valuable insights to the evolving landscape of treatment options for this rare and intricate cardiovascular condition.
Keywords
Eisenmenger Syndrome, Inhaled Nitric Oxide, Hypoxemia
References
Steudel W, Hurford E. WE, Zapol WM (1999) Inhaled nitric oxide:Basic biology and clinical applications. Anesthesiology 91(4):1090–121.
Anas M, Triastuti N, Airlangga MP (2020) Role of Inhaled Nitric Oxides In Pregnancy With Eisenmenger Syndrome. Qanun Med J Fac Med Muhammadiyah Surabaya 4(1):11–26.
Anggard E (1994)Nitric Oxide: mediator, murderer, and medicine. Lancet 343:1199–206.
Atz AM, Wessel DL (1997) Inhaled nitric oxide in the neonate with cardiac disease. Semin Perinatol 21(5):441–55.
5. Chen C (1997) Nitric Oxide For Newborns Nitric Oxide Proves Effective In Treating Newborns With Life-Threatening Lung Disorder [Internet]. Available from: cwchen@ITSA.UCSF.EDU
Finer NN, Barrington KJ (1997) Nitric oxide in respiratory failure in the newborn infant. In: Seminars in Perinatology. Elsevier, p. 426–40.
Barrington KJ, Finer N, Pennaforte T, Altit G (2017) Nitric oxide for respiratory failure in infants born at or near term. Cochrane Database Syst Rev. 2017(1): 1-9.
8. Smith C (1984) Congenital heart disease, with special reference to the indications and. In: Hahnemann monthly. 6th Editon. Appleton & Lange, p. 208–14.
9. Vaishnava H (1957) Heart diseases in pregnancy. InJournal of the Indian Medical Association, 6th Editon. Appleton & Lange, p. 228–33.
10. Barry AP, Meagher D, O’dwyer E (1956) Heart disease in pregnancy. In: Journal of the Irish Medical Association. 8th Editio. McGraw-Hill, Inc., p. 82–3.
11. Brennan K, Hatch DM (2018) Eisenmenger’s Syndrome. In: Consults in Obstetric Anesthesiology. Switzerland: Springer Nature, p. 185–7.
12. Gibbs CP (1988) Anesthetic Management of High-Risk Mother. In: Sciarra Gynecology and Obstetrics. J. B. Lippincott Company, p. 1–11.
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