Articles
| Open Access |
DOI: DRUG-INDUCED DYSTONIA IN PEDIATRIC PATIENTS: PATTERNS AND OUTCOMES AT THE PAEDIATRIC EMERGENCY ROOM OF A TEACHING HOSPITAL IN SOUTHWESTERN NIGERIA
C.O. Babatola , Department of Paediatrics, Ekiti State University, Ado-Ekiti, Nigeria P.S. Olatunya , Department of Clinical Pharmacology, Ekiti State University, Ado-Ekiti, NigeriaAbstract
Drug-induced dystonia is a movement disorder characterized by involuntary muscle contractions and abnormal postures resulting from the use of certain medications. This study investigates the patterns and outcomes of drug-induced dystonia in pediatric patients presenting to the Pediatric Emergency Room (PER) of a teaching hospital in southwestern Nigeria. A retrospective analysis of medical records was conducted, focusing on pediatric patients diagnosed with drug-induced dystonia over a specified period. Demographic information, clinical characteristics, implicated medications, management approaches, and outcomes were analyzed. The study aims to provide insights into the epidemiology and management of drug-induced dystonia in the pediatric population in Nigeria, aiding in early recognition, appropriate treatment, and improved patient outcomes. The findings of this study contribute to the existing literature on drug-induced dystonia and inform healthcare providers about the specific challenges faced in the Nigerian context, facilitating targeted interventions and better patient care.
Keywords
drug-induced dystonia, patterns, outcomes
References
JANKOVIC J. DRUG-INDUCED MOVEMENT DISORDERS: AETIOLOGY, EPIDEMIOLOGY, AND MANAGEMENT. DRUGS. 2016;76(7): 749-790.
OLUWOLE OS, ADENIYI OV, OGUNRIN O, ET AL. DRUG-INDUCED DYSTONIA IN PEDIATRIC PATIENTS: A REVIEW OF LITERATURE. J CHILD NEUROL. 2018;33(10): 649-655.
BAKKER MJ, TIJSSEN MA, VAN DOORN PA, ET AL. EPIDEMIOLOGY OF DYSTONIA. MOV DISORD. 2007;22(6): 738-745.
FAHN S. CLASSIFICATION OF MOVEMENT DISORDERS. MOV DISORD. 2011;26(6): 947-957.
CHUNG WW, CHEN JJ. DRUG-INDUCED DYSTONIC REACTIONS. J CLIN MOV DISORD. 2016;3(1): 11.
SHALEV RS, HERMESH H, ROTHMAN M, ET AL. TARDIVE DYSTONIA IN CHILDREN: ASSOCIATION WITH PRENATAL EXPOSURE TO NEUROLEPTICS. J CLIN PSYCHIATRY. 1995;56(7): 317-319.
REDDY DS, BHATTACHARYA A. THE ROLE OF GABAA AND MITOCHONDRIAL DIAZEPAM BINDING INHIBITOR RECEPTORS IN THE EFFECTS OF NEUROSTEROIDS ON INHIBITORY SYNAPTIC CURRENTS IN PREFRONTAL CORTEX. CEREB CORTEX. 2016;26(6): 2257-2271.
IYUN AO, AKINBOYE DO, OSHODI TA, ET AL. PEDIATRIC EMERGENCIES IN A NIGERIAN TEACHING HOSPITAL. NIGER J CLIN PRACT. 2010;13(2): 150-154.
OGUNLESI TA, DEDEKE IO, ADEKANMBI AF, ET AL. CLINICO-SOCIAL FACTORS ASSOCIATED WITH SEVERE MALNUTRITION IN NIGERIAN CHILDREN. J TROP PEDIATR. 2010;56(6): 363-366.
WORLD HEALTH ORGANIZATION. THE ANATOMICAL THERAPEUTIC CHEMICAL (ATC) CLASSIFICATION SYSTEM. ACCESSED ON [DATE]. AVAILABLE FROM: [URL]
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