★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★Open research. Global perspectives.
Medical Sciences OPEN ACCESS

Clinical Cases Of Hepatitis-Associated Aplastic Anemia

Makhmudov Ravshan Barraevich
Bukhara State Medical Institute, Uzbekistan
Safarova Gulnoz Avazkhonovna
Bukhara State Medical Institute, Uzbekistan
tajmspr 2021
VOL. 3 / NO. 04 APRIL
VOLUME 3
ISSUE 04
YEAR 2021
PAGES 195-199

Abstract

The article presents two cases of hepatitis-associated aplastic anemia in the last year. The literature data on the new nosology are presented. The clinical picture, diagnosis and treatment are discussed. The questions of diagnosis and treatment that affect the prognosis are raised. Treatment preference should be given to allogeneic bone marrow transplantation, as it has better results than aggressive immunosuppressive therapy that is difficult for patients to tolerate.

Keywords

Hepatitis-associated aplastic anemia immunosuppressive therapy

Downloads

Download data is not yet available.

References

  1. Kosterina A.V., Nazipova Z.M., Marapov D.I. The effectiveness of the use of immunosuppressive therapy and splenectomy in the treatment of patients with aplastic anemia on the example of the experience of the Department of Hematology of the RCH // Practical Medicine. - 2016. - No. 4 (96). - S. 68-72. [in russian]
  2. Brown K.E., Tisdale J., Barrett A.J., et al. Hepatitis-associated aplastic anemia // N. Engl. J. Med. ― 1997. ― 336. ― P. 1059.
  3. Osugi Y., Yagasaki H., Sako M., et al. Antithymocyte globulin and cyclosporine for treatment of 44 children with hepatitis associated aplastic anemia // Haematologica. ― 2007. ― 92. ― P. 1687.
  4. Ohara A., Kojima S., Okamura J., et al. Evolution of myelodysplastic syndrome and acute myelogenous leukaemia in children with hepatitis-associated aplastic anaemia // Br. J. Haematol. ― 2002. ― 116. ― P. 151.
  5. Савченко В.Г. Клинические рекомендации по лечению апластической анемии // Национальное гематологическое общество. ― 2014. ― С. 8-22.