Articles
| Open Access | Advances in Cervical Vertebral Augmentation: The Role of PTH Derivative Bioactive Materials in Sheep Models
Arthur Billeter , Graduate School for Cellular and Biomedical Sciences, University of Bern, SwitzerlandAbstract
Cervical vertebral augmentation is a crucial procedure for addressing vertebral defects and promoting bone regeneration, particularly in the context of spinal injuries and degenerative diseases. Recent advancements in bioactive materials have opened up new possibilities for enhancing the efficacy of vertebral augmentation. This study investigates the role of parathyroid hormone (PTH) derivative bioactive materials in cervical vertebral augmentation using a sheep model. PTH derivatives have shown promising results in bone regeneration due to their osteoinductive properties, which stimulate the activity of osteoblasts and enhance bone formation. In this study, a sheep model was utilized to evaluate the effects of PTH derivative bioactive materials on cervical vertebral healing, focusing on parameters such as bone mineral density, structural integrity, and histological outcomes. The results demonstrated that PTH derivative bioactive materials significantly improved the healing process of cervical vertebral defects, providing insights into their potential clinical applications in spinal surgeries. The findings suggest that PTH-based bioactive materials could play a vital role in enhancing the success of cervical vertebral augmentation, offering a promising approach for regenerative medicine in spinal health.
Keywords
Cervical vertebral augmentation, PTH derivatives, bioactive materials
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