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DOI: INTERPLAY OF RENAL HISTOPATHOLOGY, BLOOD UREA NITROGEN, AND CREATININE LEVELS IN RATS WITH UNILATERAL URETERAL OBSTRUCTION: A COMPREHENSIVE ANALYSIS
Bambang Arifianto , Department of Clinical Pathology Faculty of Veterinary Medicine Universitas Gadjah Mada, Indonesia Dhirgo Rickyawan , Department of Surgery and Radiology Faculty of Veterinary Medicine Universitas Gadjah Mada, IndonesiaAbstract
This study investigates the intricate relationship between renal histopathology, blood urea nitrogen (BUN), and creatinine levels in rats subjected to unilateral ureteral obstruction (UUO). A comprehensive analysis was conducted to discern the interplay among these factors and understand the implications for renal function. Rats with induced UUO were closely monitored, and renal tissues were examined for histopathological alterations. Simultaneously, BUN and creatinine levels were measured to assess renal dysfunction. The results revealed a complex interdependence, shedding light on the nuanced connections between structural changes, biomarker levels, and the severity of renal impairment in the context of UUO. This comprehensive analysis contributes valuable insights to our understanding of renal pathophysiology and lays the groundwork for potential therapeutic interventions.
Keywords
Renal histopathology, blood urea nitrogen, creatinine levels
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