The article examines the use of ozone in the surgical treatment of common appendicular peritonitis in children. The use of ozone in clinical medicine is based on its oxidative, antioxidant, disinfectant, bactericidal, detoxifying, immunocorrecting, antihypoxic. An experimental model of peritonitis was created on 41 white Wistar rats of both sexes. Morphological studies of the effect of ozone therapy on the course of peritonitis in experimental animals allowed us to establish the high effectiveness of this method in the treatment of purulent-inflammatory processes in the abdominal cavity and the prevention of the formation of adhesions, which was the basis for the use of ozone in clinical practice.

The works show that, using fluorescent probes, it was used to study the effect of PC-8 on changes in the dynamics of the intracellular Ca²⁺ content in synaptosomes of the rat brain, depending on the site of the binding of glutamate on calcium channels by a specific mediator with glutamate. To measure the amount of cytosolic Ca²⁺ synaptosomes, we calculated using the Grinkevich equation. It has been shown that polyphenol PC-8 binds to the glutamate-binding site of NMDA receptors, so that the conductance for Ca²⁺ ions is reduced through a channel blocking the effect of polyphenol PC-8 can be explained. due to its binding to the competing action of the site, the binding of glutamate to NMDA receptors.

In this scientific article, the Republican Specialized Scientific and Practical Medical Center of Oncology and Radiology of the Andijan Regional Department conducted a comparative analysis of the survival rate of 1825 patients with primary disability in 2017 and those who for some reason did not form. The results of the analysis showed that disability benefits had a positive effect on patients who developed disabilities at 12, 12-24 months and 24-36 months of age and, as a result, led to improved survival rates. All results are statistically processed on a standard basis.

The relevance of the topic is determined by the increase in morbidity among the child population. Bronchial asthma is one of the most common childhood diseases, a formidable complication of which is asthmatic status, as well as the fact that the timely treatment of the disease, taking into account its severity and characteristics, the use of modern effective drugs are the key to the success of therapy, allow you to quickly stabilize the child's condition and further control bronchial asthma.

The health of the population, its preservation and strengthening, an increase in life expectancy and a reduction in mortality have always been and remain the focus of state social policy. However, it is known that human health depends not only on the quality of medical care, but also on many other factors, such as genetic predisposition to certain diseases, the state of the environment and lifestyle. According to experts from the World Health Organization, the combined contribution of medical care and hereditary factors to health is no more than 30%, while 50% is a healthy lifestyle.

Need and Reason To discover the viability of neural activation in lessening torment and expanding practical capacity in patients with cervical radiculopathy. Study Plan arbitrary inspecting Member's 30 subjects enrolled from various wellbeing habitats and clinics. Result Measures: NTRS (Neumari torment rating scale), PEPS (patient explicit practical scale) Result: the impact of treatment is critical for both gathering An and bunch B by utilization of Pre and Post PEPS . Here t esteem is measurably huge with p esteem (.000) in bunch An and p esteem (.000) in bunch B. So for both the gathering the impacts of the treatment are measurably critical. End: On examination of relationships we tracked down that Neural Assembly alongside Neck practice is more viable than just neck practice surveyed by utilizing PEPS  and NTRS.

"Perfection is achieved not when there is nothing to add, but when there is nothing to remove" Antoine de Saint-Exupery Presents the results of a study of the performance of aesthetic and artistic restorations and the study of these dental restorations after a certain time with the naked eye and binoculars of two types, while the use of a SLR camera was a prerequisite. Comparative analysis has shown that the use of optical systems during dental manipulations significantly improves the diagnosis of carious and non-carious lesions, facilitates work and reduces the risk of various complications. Clinical photographs are an important component of aesthetic dentistry.

Unique Injury therapy is one of the significant territories in clinical and nursing practice that has stood out of wellbeing experts in view of the rising occurrence of constant injuries combined with their various related financial outcomes to people and governments. The target of this work was to research the adequacy and patient's Experiences  of worm treatment in the treatment of wounds. A Precise survey of subjective and quantitative examination writing was received for this work. Seven electronic data sets were efficiently looked through utilizing applicable catchphrases. An aggregate of 17 articles which met the incorporation models were chosen and basically evaluated and broke down utilizing CASP apparatus. Seventeen investigations were evaluated to find out the adequacy and patient's Experiences  of worm treatment. The discoveries for adequacy of Maggot treatment show that worm treatment is better in injury debridement contrasted with customary treatment. Patients treated with Maggot treatment had differed Experiences  of agony, shivering sensation, loss of craving, creepy sentiments and tingling.

The article provides a review of the literature devoted to modern data, as well as the impact of genetic predisposition on the development of pneumonia in children. It is known that timely, innovative diagnosis, treatment and prevention of pneumonia in children today is one of the most pressing problems in pediatrics. Timely identification of the etiological cause of pneumonia, treatment is carried out only by early diagnosis, adequate assessment of the severity of the patient's condition, reasonable choice of treatment with antibiotics, taking into account the background disease, age and weight of the child.

In this article, opinions were expressed on the improvement of early-stage diagnostic factors and the optimal pathways of therapeutic treatment, having determined the characteristics of heterogeneous neurohumorals of metabolic syndrome, the clinical manifesto of the disease. The analysis of the study shows that the issues of pathogenesis, clinical features of improving the effectiveness of medicamentous therapy, and treatment-rehabilitation aspects have not been studied perfectly so far. In patients with metabolic syndrome, hypotensive, anti-adipose agents, as well as treatment of statins and improvement of the prophylactic order of prevention of diseases, the issues of which were not studied at the end were discussed.

The article under discussion depicts TORCH infections as an actual problem in obstetrics and gynaecology practice. The author of the article considers that the course of the disease is often asymptomatic, and the pathological impact of the causative agents on the embryonic development of the fetus leads to the development of defects, which cause spontaneous abortions, perinatal and postnatal deaths, as well as a disability at a young age.

Among the production of harmful industry all over the world, including in our repub-lic, tobacco production occupies a significant place. In Uzbekistan, tobacco cultivation is car-ried out by workers of the Urgut district of the Samarkand region, which accounts for a large share in agriculture and brings significant economic profit.

The available literature does not cover the issue of the effect of tobacco dust and pes-ticides in combination with uncomfortable microclimatic conditions on the organs and tissues of the oral cavity of tobacco growers.

Some aspects of the mechanism of development of pathological changes in the oral cavity of tobacco growers are not specified in the conditions of Uzbekistan, and accordingly there is no data on adequate methods of their prevention and treatment [1,3]. In this regard, there is a need to study the features of the clinic and the course of the main dental diseases in tobacco growers in order to develop a set of organizational, sanitary, hygienic and therapeutic and preventive measures aimed at improving the quality of the production environment, pre-venting the development and reducing the frequency of dental morbidity among tobacco growers.

The purpose of the study is to study the correlation rate of the quality of life, electroneuromyography, doppler and neuro markers BNDF in the blood in patients with a type 2 of type with diabetic foot syndrome.

Methods: The following 2 groups of patients were formed: 1 gr. - SDS patients, neuropathic form -37 patients, 2 gr. - SDS patients, neuroichmic form -35 patients, 3 gr. - Control group, these are 20 healthy persons of the appropriate age and gender.

Results: In all groups of patients, the quality of life is significantly different in the FSHC questionnaire compared with the control group (p <0.05). In patients with a neuroecemic form of diabetic foot syndrome, a significant decrease was found (p <0.05). All indicators of doppler song vessels of legs compared with patients with neuropathic shape.

Revealed significant correlations of FSHK and laboratory and instrumental indicators. A correlation connection with the duration of the disease, the duration of the disease, the levels of glycemia of an empty stomach, the level of the glycated haemoglobin, BNDF in the blood, the speed of blood flow in the femoral artery, in the lower leg, is discovered.

The definition of neuromuscular transmission showed that the patients of the 1st and 2nd groups have a weak reduction in muscle contraction involuntarily. This confirmed the impairment of neuromuscular transmission in both groups.

Conclusions: 1) A questionnaire to determine the quality indicators - FSHK is the most sensitive and informative to determine the quality of life in patients with type 2 diabetes mellitus with neuropathic and neuroecemic forms

2) FSHP questionnaire can be used for dynamic assessment of type 2 diabetes patients with neuropathic and neuroecemic forms in outpatient clinical practice.

3) Revealed significant correlations of FSHK and laboratory and instrumental indicators. A correlation connection with the duration of the disease, the duration of the disease, the levels of glycemia on an empty stomach, the level of the glycated haemoglobin, BNDF in the blood, the speed of blood flow in the femoral artery, in the shin, M-answer when stimulating a tibial nerve.