Medical Science
| Open Access |
DOI: Long-Term Ecological Stress And Pathomorphological Changes In The Myocardium
Farida Azizova , Doctor of Sciences (DSc), Associate Professor, Department of Functional Diagnostics, Center for the Professional Qualification Improvement of Medical Workers, UzbekistanAbstract
The article examines the impact of long-term ecological stress on the morphological condition of the myocardium. It presents data indicating the development of structural changes in heart muscle tissue under the influence of environmental pollutants such as particulate matter, nitrogen oxides, heavy metals, and toxic compounds. Special attention is given to pathomorphological changes — myolysis, interstitial fibrosis, mitochondrial dysfunction, and epigenetic alterations. The importance of early diagnosis and preventive strategies is emphasized in the context of a deteriorating environmental situation.
Keywords
Myocardium, ecological stress, pathomorphology
References
Куликов Л. В. Морфология миокарда при хронической ишемической болезни сердца / Л. В. Куликов. — М.: Медицина, 2012. — 192 с.
Барков В. А. Патоморфологические изменения сердца при воздействии факторов внешней среды // Вестник морфологии. — 2020. — Т. 26, № 2. — С. 43–50.
Pope C.A., Dockery D.W. Health effects of fine particulate air pollution: lines that connect // J. Air & Waste Manage. Assoc. — 2006. — Vol. 56, No. 6. — P. 709–742.
Brook R.D. et al. Air pollution and cardiovascular disease: a statement for healthcare professionals from the Expert Panel on Population and Prevention Science of the American Heart Association // Circulation. — 2010. — Vol. 121, No. 21. — P. 2331–2378.
Зайцева Т. В. Эпигенетические механизмы адаптации миокарда к стрессу // Кардиология. — 2021. — Т. 61, № 3. — С. 34–41.
Xu X., Wang A., Chen L.C., et al. Long-term exposure to ambient air pollution and the onset of heart failure: a study of cellular mechanisms // Environmental Health Perspectives. — 2011. — Vol. 119, No. 10. — P. 1242–1248.
WHO. Ambient (outdoor) air pollution. World Health Organization Fact Sheets. — Geneva, 2021. URL: https://www.who.int/news-room/fact-sheets/detail/ambient-(outdoor)-air-quality-and-health
Article Statistics
Downloads
Copyright License
Copyright (c) 2025 Farida Azizova
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors retain the copyright of their manuscripts, and all Open Access articles are disseminated under the terms of the Creative Commons Attribution License 4.0 (CC-BY), which licenses unrestricted use, distribution, and reproduction in any medium, provided that the original work is appropriately cited. The use of general descriptive names, trade names, trademarks, and so forth in this publication, even if not specifically identified, does not imply that these names are not protected by the relevant laws and regulations.