The number of patients with diabetes mellitus in the Andijan region who were registered according to endocrinologists from 2000 to 2015 increased almost fourfold from 26,000 to more than 110,000 in 2016 (14). This also shows that the number of patients with various purulent-necrotic complications of diabetes mellitus also increases proportionally, in addition, there is an increase in patients with severe purulent-septic complications of these processes, with widespread, deep purulent-necrotic fasciitis [3]. Of patients in the department of surgical infection of the ASMI clinic, patients with purulent-necrotic complications of diabetes mellitus account for almost 78%, which indicates a significant increase in the number of these patients. This tendency continues and goes up every year. According to the WHO, by 2030 every 15 people will have diabetes, and by 2050 this figure will be equal to every 6 people.

Purulent-Necrotic, tissues and tendon, WHO, antibiotic-resistant microflora

Abdullaev RN / Complex treatment of purulent-necrotic lesions of the lower extremity in patients with diabetic foot syndrome. // New day in medicine. 2021 No. 2 (34), p.413-417.

Abdullaev R.N., Yusupov K.A., Abdullaeva M.A. et al. / Application of prolonged action enzymes impregnated on synthetic materials for cleansing necrotic wounds. // In the collection Actual problems of modern medicine. Medicine today, tomorrow. Republican conference with international participation. 2018. pp. 603-604. {{ 1}}

Abdullaev S.A., Musaev S.T. / Surgical treatment of necrotizing fasciitis in patients with diabetes. // Collection of scientific papers Diabetes mellitus, its complications and surgical infections. - Practical Congress, Moscow, 2019. November 19-21. Moscow. Publishing "Pero" -108 p.3-4.

Babadzhanov B.D., Islamov M.S., Zhanabaev B.B. et al. / Application of long-term intra-arterial catheter therapy in the treatment of purulent-necrotic lesions of the foot in patients with diabetes mellitus // Pathology. –2000.- № 4.- P. 52-54.

Bazlova SB / Complex treatment of purulent-necrotic lesions of the lower extremity in patients with diabetes mellitus against the background of decompensated ischemia. // Successes of modern natural science. 2005. No. 9. Pp. 89-90.

Belyaeva OA, Radzikhovsky AP, Krizhevsky et al. / Results of studies of the degree of ischemia in diabetic foot. // Academy of electr. Publications. Kiev. 2012 No. 1 (87) 1-P. P.L. Shupik National Medical Academy of Postgraduate Education.

Musashaikhov Kh.T., Ikramova F.D., Vasilevsky E.A. and etc./ Complex treatment of patients with purulent-necrotic lesions of the foot in patients with diabetes mellitus. // Tibbiyotda yangi kun 2018 # 3.455-461

Tarakanova OE / Complex treatment of patients with purulent-necrotic complications of diabetic foot syndrome. // Dissertation for the degree of candidate of medical sciences, Nizhny Novgorod 2008, 122 pages.

Tarakanova O.E., Smirnov I.F. / Non-clostridial anaerobic infection in the purulent department of the city hospital. // Wounds. Wound infection. Mat. 1V All-Russian Conference of General Surgeons with International Participation and the Plenum of the Problem Commission "Infection in Surgery". Yaroslavl, 2007. pp. 183-185.

Tarakanova OE, Kurykin MI, Kleshkin A. E. / A new approach to the treatment of chronic arterial insufficiency. // Outpatient surgery No. 28.20076, p. 116.

Tartakovsky EA, Gvozdev NA. et al. Treatment of complications of “diabetic foot” // Surgery. - 2009. - No. 10. - P. 53-55.

Tolstykh P.I., Ivanyan A.N., Geynits A.V. et al. // Little secrets of the use of laser radiation in the prevention and treatment of purulent wounds. M., 2009 59 pp.

Prokhorov A.V., Dushkevich V.S. Treatment of wet foot gangrene in patients with diabetes mellitus // Surgery. - 2011. - N7. - S. 11-14.

Khatamov E.A., Khatamov M.E. / Peculiarities of studying the epidemiology of patients with diabetes mellitus in the Andijan region. // Materials of the Republican conference of endocrinologists of Uzbekistan with international participation. Tashkent city, 2017 P.96-97.

Shiryaev V.S. Bugrovsky O.N., Shvetsky F.M. et al. / Treatment of purulent-necrotic processes with the use of intravenous laser region. blood (405 nm.). // Collection of scientific tr.Diabetes mellitus, its complications and surgical infections. Materials of the 4th International Scientific and Practical Congress. Moscow, 2019. 19-21 November. Moscow. Publishing "Pero" -108p. 96-99p.

Chur N.N. / Treatment of patients with chronic lower limb ischemia in diabetes mellitus. // Surgery News, 2008, No. 16 (1), p.61-66.

Hitoshu Nukada / Diabetic Microangiopathy - an overview I ScienctDirect Topics - // Amer.J.Med. - 2006. - Vol.85, N5A. - p. 119-130.

Camera A. / Diabetic Microangiopathy: physiopatological, clinical and therapeutic aspectis // Minerva Endocrinolog. 2007. sep. Pub / Med.

Wagner F.W. The diabetic foot.//Ortopedics.-2005.-N 10.-p.163-171.