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DOI: ASSESSMENT OF THE DYNAMICS OF HEPATIC ENCEPHALOPATHY IN PATIENTS WITH CIRRHOSIS BEFORE AND AFTER IN-HOSPITAL TREATMENT
Bekmuradova Makhsuda Salkhidinovna , Department of Propaedeutics of Internal Diseases, Samarkand State Medical Institute, Uzbekistan Khaydarov Sanjar Nizomitdinovich , Department of Propaedeutics of Internal Diseases, Samarkand State Medical Institute, UzbekistanAbstract
Hepatic encephalopathy (HE) is a frequent complication of liver dysfunction, including acute liver failure and cirrhosis. HE presents with a sHEctrum of neuropsychiatric symptoms ranging from mild cognitive impairment to coma. The diagnosis of HE is based on the characteristic anamnestic, clinical and paraclinical findings and requires the exclusion of other causes of encephalopathy . Psychometric tests are widely used in clinical practice for the early diagnosis of HE: number-letter, number- line, handwriting, arithmetic etc. The sensitivity of psychometric tests in detecting HE is 70-80%. Although less severe, patients with minimal hepatic encephalopathy are at significant risk for impaired quality of life, including increased hospitalisation and progression to manifest HE. The main aim of our study is to compare and evaluate the extent and dynamics of HE in patients with cirrhosis before and after inpatient treatment.
Keywords
Liver cirrhosis, hepatic encephalopathy, blood ammonia
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