Articles | Open Access | DOI: https://doi.org/10.37547/TAJMSPR/Volume02Issue11-10

Primary Diagnosis Of Acquired Thrombocytopathy In Family Polyclinics

Dadajanov Utkir Dadajanovich , Associate Professor, Head Of The Department Department Of Hematology, Candidate Of Medical Sciences, Samarkand State Institute, Uzbekistan
Abdiev Kattabek Makhmatovich , Associate Professor Of The Department Of Hematology, Candidate Of Medical Sciences, Samarkand State Institute, Uzbekistan

Abstract

The article is devoted to general issues of classification and differential diagnosis of thrombocytopathy. Features of pathogenesis, clinical course and diagnosis of certain rare inherited thrombocytopathies are highlighted. Particular attention is paid to the formation of the molecular basis of these diseases. The basic genetic mutations associated with a number of thrombocytopathies are given.

Keywords

Platelets,, rare inherited hematologic disorders

References

mutation in patients with Glanzmann thrombasthenia located in the N-terminus of blade 1 of the betapropeller (Asn2Asp) disrupts a calcium binding site in blade 6. J Thromb Haemost 2011;

Raccuglia G. Grey platelet syndrome:a variety of qualitative platelet disorder. Am J Med 1971.

Gerrard J. M., Phillips D. R., Rao G. H.. Biochemical studies of two patients with the grey platelet syndrome. J Clin Invest 1980;

Levy-Toledano S., Caen J. P.,Breton-Gorius J. et al. Gray platelet syndrome: alpha-granule deficiency. Its influence on platelet function. J Lab Clin Med 1981;

Nurden A. T., Kunicki T. J., Dupuis G.et al. Specific protein and glycoprotein deficiencies in platelets isolated from two patients with the grey platelet syndrome. Blood 1982;

Article Statistics

Copyright License

Download Citations

How to Cite

Dadajanov Utkir Dadajanovich, & Abdiev Kattabek Makhmatovich. (2020). Primary Diagnosis Of Acquired Thrombocytopathy In Family Polyclinics. The American Journal of Medical Sciences and Pharmaceutical Research, 2(11), 57–61. https://doi.org/10.37547/TAJMSPR/Volume02Issue11-10