Articles
| Open Access | Comet Measure To Screen Cell Line Maturing
Khloud M. Alhozali, Al Anazi Almaimani , Department Of Microbiology And Immunology, College Of Pharmacy, King Saud University, Saudi ArabiaAbstract
'Comet test' turns into an amazing asset in bioassay and cell lines are the favored
investigation frameworks in the light of tough bioethic standards. Human B lymphocytedetermined cell lines at various section levels were exposed to antacid comet test. Cell lines
at higher sections showed expanded DNA harm contrasted with that of lesser entries. What's
more, apoptotic conditions were likewise discovered more at higher entries. At the point
when cell lines were exposed to illumination (2 Gy of 60Co-γ), the tailmoment produced
because of the radiation-affront was seen as affected by section factor. In this way 'section
factor' can force for fitting remedy estimates when cell lines are utilized in genotoxic test.
Single cell gel electrophoresis can be a straightforward technique to evaluate the
appropriateness of a given cell line for toxicological investigations.
Keywords
Cell line,, Comet measure,
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Copyright (c) 2020 Khloud M. Alhozali, Al Anazi Almaimani
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