Clinical Features of Respiratory Distress Syndrome in Preterm Neonates
Abstract
Respiratory distress syndrome (RDS) is one of the most common and severe disorders of the early neonatal period in preterm infants.
Objective: to investigate the clinical features of respiratory distress syndrome in preterm neonates according to gestational age.
Materials and Methods: The study included 60 neonates with RDS. Their gestational age ranged from 26 to 37 weeks. A general clinical examination was performed. The clinical severity of respiratory distress was assessed using the Silverman/Downes score.
Results: The incidence of severe birth asphyxia was two- to threefold higher among preterm neonates born at 26-28 weeks of gestation than among those born at 29-37 weeks. Assessment using the Silverman score showed that 94.7% of preterm neonates born at 26-28 weeks had extremely severe RDS, a substantially higher proportion than in the groups born at 29-37 weeks. In preterm neonates born at 33-37 weeks, RDS was predominantly mild.
Keywords
Neonate, prematurity, respiratory distress syndrome
References
Sweet D.G., Carnielli V.P., Greisen G., Hallman M., Klebermass-Schrehof K., Lavizzari A., et al. European Consensus Guidelines on the Management of Respiratory Distress Syndrome: 2025. Neonatology. 2026;123(4):514-539. doi:10.1159/000551062.
Tana M., Tirone C., Aurilia C., Lio A., Paladini A., Fattore S., et al. Respiratory Management of the Preterm Infant: Supporting Evidence-Based Practice at the Bedside. Children (Basel). 2023;10(3):535. doi:10.3390/children10030535.
Chen I.L., Chen H.L. New developments in neonatal respiratory management. Pediatrics & Neonatology. 2022;63(4):341-347. doi:10.1016/j.pedneo.2022.02.002.
De Luca D. Respiratory distress syndrome in preterm neonates in the era of precision medicine: A modern critical care-based approach. Pediatrics & Neonatology. 2021;62(Suppl 1)-S9. doi:10.1016/j.pedneo.2020.11.005.
Zavyalov O.V., Chabaidze Zh.L., Dementyev A.A., Pasechnik I.N. Respiratory distress syndrome in extremely preterm infants: epidemiology, pathogenesis, clinical manifestations, and perinatal risk factors. Vrach. 2020;31(8):24-31. doi:10.29296/25877305-2020-08-04.
Mostovoy A.V., Karpova A.L., Volodin N.N., Petrova A.S., Mileva O.I., Zakharova N.I., et al. Assessment of respiratory-therapy practices and outcomes in preterm neonates born at 34-36 weeks with respiratory distress syndrome. Anesteziologiya i Reanimatologiya. 2021;(4):67-72. doi:10.17116/anaesthesiology202104167.
Navruzova Sh.I., Yuldasheva G.G. Efficacy of surfactant therapy in preterm infants with respiratory distress syndrome. International Journal of Scientific Pediatrics. 2022;1(6):14-19. doi:10.56121/2181-2926-2022-6-14-19.
Raimondi F., Migliaro F., Corsini I., Meneghin F., Dolce P., Pierri L., et al. Lung Ultrasound Score Progress in Neonatal Respiratory Distress Syndrome. Pediatrics. 2021;147(4). doi:10.1542/peds.2020-030528.
Chistyakova G.N., Remizova I.I., Kadochnikova P.A., Abakarova D.A. Clinical and immunological criteria for the development of respiratory distress syndrome in newborns. Doctor.Ru. 2025;24(3):19-24. doi:10.31550/1727-2378-2025-24-3-19-24.
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Copyright (c) 2026 Khodjamova N.K., Nazarova G.

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