Effects of Intradialytic Exercise on Cardiac Biomarkers in Patients Undergoing Maintenance Hemodialysis
Kasimova Guzal Botirovna , PhD, Assistant of the Department of Internal Medicine, Nephrology and Hemodialysis, Tashkent State Medical University. Tashkent, Uzbekistan Republican Specialized Scientific and Practical Medical Center of Nephrology and Kidney Transplantation. Tashkent, UzbekistanAbstract
Cardiovascular complications remain the leading cause of morbidity and mortality in patients with Chronic Kidney Disease receiving maintenance hemodialysis. Elevated cardiac biomarkers, including troponin and N-terminal pro–B-type natriuretic peptide (NT-proBNP), are associated with subclinical myocardial injury and poor cardiovascular outcomes. Intradialytic physical exercise has recently gained attention as a potential non-pharmacological strategy for improving cardiovascular health in hemodialysis patients.
Keywords
Maintenance hemodialysis, intradialytic exercise, cardiac biomarkers
References
Sharapov O., Daminov B. Cardiovascular Diseases in Dialysis Patients at Different Levels of Healthcare of the Republic of Uzbekistan. Central Asian Journal of Nephrology. 2025;1(1):cajn001. DOI: 10.63946/cajn/16627.
Sharapov O.N., Daminov B.T., Yarygina S. Cardiovascular pathologies in the urban population of the Republic of Uzbekistan with chronic kidney disease on hemodialysis. KIDNEYS. 2020;9(3):137–143. DOI: 10.22141/2307-1257.9.3.2020.211459.
Abdullaev S. Association of mortality with intradialytic exercise in patients undergoing hemodialysis. Nephrology Dialysis Transplantation. 2023;38(Suppl 1):gfad063d_3055.
Daminov B.T. Cardiovascular disease in patients with chronic kidney disease receiving hemodialysis. Samarkand State Medical University Scientific Materials. 2017.
Sharapov O., Daminov B. Cardiovascular risk and structure of cardiovascular diseases in dialysis patients in Uzbekistan. Central Asian Journal of Nephrology. 2025;1(1):cajn001. DOI: 10.63946/cajn/16627.
Sheng K., Zhang P., Chen L., Cheng J., Wu C., Chen J. Intradialytic exercise in hemodialysis patients: a systematic review and meta-analysis. American Journal of Nephrology. 2014;40(5):478–490. DOI: 10.1159/000368722.
Peters C.D., Kjaergaard K.D., Christensen K.L., Bibby B.M., Jespersen B., Jensen J.D. High-sensitivity troponin T in hemodialysis patients. BMC Nephrology. 2020;21:304. DOI: 10.1186/s12882-020-02103-1.
Pu J., Jiang Z., Wu W., Li L., Zhang L., Li Y., Liu Q., Ou S. Efficacy and safety of intradialytic exercise in haemodialysis patients: a systematic review and meta-analysis. BMJ Open. 2019;9:e020633. DOI: 10.1136/bmjopen-2017-020633.
Verrelli D., et al. Effect of intradialytic exercise on cardiovascular outcomes in hemodialysis patients. 2024.
Wang Y., et al. Association of N-terminal pro-brain natriuretic peptide with volume status and cardiac function in hemodialysis patients. Frontiers in Cardiovascular Medicine. 2021;8:646402. DOI: 10.3389/fcvm.2021.646402.
Download and View Statistics
Copyright License
Copyright (c) 2026 Kasimova Guzal Botirovna

This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors retain the copyright of their manuscripts, and all Open Access articles are disseminated under the terms of the Creative Commons Attribution License 4.0 (CC-BY), which licenses unrestricted use, distribution, and reproduction in any medium, provided that the original work is appropriately cited. The use of general descriptive names, trade names, trademarks, and so forth in this publication, even if not specifically identified, does not imply that these names are not protected by the relevant laws and regulations.

Medical Science
| Open Access |
DOI: