★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★Open research. Global perspectives.
Medical Science OPEN ACCESS

Psychosocial and Environmental Determinants of Psychoactive Substance Use Disorders Among Youth in Nigeria: A Systematic Review

Kennedy Oberhiri Obohwemu
PhD, Department of Interdisciplinary Research and Statistics, PENKUP Research Institute, Birmingham, United Kingdom.
Gordon Mabengban Yakpir
PhD, Faculty of Health, Wellbeing & Social Care, Oxford Brookes University, GBS Partnership, Birmingham Campus, United Kingdom; and PENKUP Research Institute, Birmingham, United Kingdom
Kenneth Oshiokhayamhe Iyevhobu
MPH, Department of Medical Laboratory Science, Faculty of Applied Health Science, Edo State University, Iyamho, Edo State, Nigeria; Department of Medical Microbiology, Faculty of Medical Laboratory Science, Ambrose Alli University, Ekpoma, Edo State, Nigeria; and Department of Interdisciplinary Research and Statistics, PENKUP Research Institute, Birmingham, United Kingdom.
Oluwafemi Emmanuel Ooju
MSc, World Health Organisation, Abuja, Nigeria; and Department of Interdisciplinary Research & Statistics, PENKUP Research Institute, Birmingham, United Kingdom.
Ulunma Ikwuoma Mariere
FWACP, Bayelsa Medical University, Nigeria; and Department of Interdisciplinary Research & Statistics, PENKUP Research Institute, Birmingham, United Kingdom.
Kevbe Ofobrukweta
PhD, Department of Health, Wellbeing & Social Care, Oxford Brookes University, GBS Partnership, Leeds, United Kingdom; and PENKUP Research Institute, Birmingham, United Kingdom.
Perpetual Ogechukwu Nwankwo
PhD, School of Public Health, University of Port Harcourt, Nigeria; and Department of Interdisciplinary Studies & Statistics, PENKUP Research Institute, Birmingham, United Kingdom
Chisom Lucky Emeka
PhD, Vaccine Preventable Diseases Unit/Health Promotion, Disease Prevention and Control Cluster, World Health Organisation Country Office, Abuja, Nigeria; and Department of Interdisciplinary Research & Statistics, PENKUP Research Institute, Birmingham, United Kingdom.
Leonard Nnamdi Meruo
MHPM, Department of Oral Diagnosis and Dental Public Health, D’ Dentist Place Dental Clinic, Owerri, Nigeria; Department of Oral Pathology, D’ Dentist Place Dental Clinic, Owerri, Nigeria; and Department of Interdisciplinary Research & Statistics, PENKUP Research Institute, Birmingham, United Kingdom.
Chinenye Cynthia Akwolu
MSc, Liverpool Women’s Hospital NHS Foundation Trust, United Kingdom; and Department of Interdisciplinary Research & Statistics, PENKUP Research Institute, Birmingham, United Kingdom.
Chiduzie Wereuche Onuoha
MBBS, St. Nicholas Hospital, Lagos, Nigeria; and Department of Interdisciplinary Research & Statistics, PENKUP Research Institute, Birmingham, United Kingdom.
Edith Chinonye Eze-Morrison
MBBS, Emergency Department, St. Peter’s Hospital Chertsey, Ashford and St. Peter’s Hospital NHS Foundation Trust, Surrey, United Kingdom; and Department of Interdisciplinary Research & Statistics, PENKUP Research Institute, Birmingham, United Kingdom.
John Chibueze Ugwu
MBBS, Family Medicine Department, Al Mandaq General Hospital, Saudi Arabia; and Department of Interdisciplinary Research & Statistics, PENKUP Research Institute, Birmingham, United Kingdom.
Nneka Chekwube Ugwu
RPHN, Medical Unit, 82 Division Military Hospital, Enugu, Nigeria; and Department of Interdisciplinary Research & Statistics, PENKUP Research Institute, Birmingham, United Kingdom.
tajmspr 2026
VOL. 8 / NO. 03 MARCH
VOLUME 8
ISSUE 03
YEAR 2026
PAGES 97-124

Abstract

Background

Substance use among adolescents and young adults is a growing public health concern in Nigeria and other low- and middle-income countries. Despite increasing prevalence, there remains limited systematic evidence on the psychosocial and environmental predictors of substance use disorders in this population. Existing studies often focus on isolated substances or risk factors, overlooking the complex interplay of determinants across developmental stages.

Methods

This systematic review synthesized findings from 22 peer-reviewed studies published between 2015 and 2025 that examined substance use among adolescents and young adults in Nigeria. Databases searched included Web of Science, PubMed and African Journals Online. Studies were selected based on relevance to psychosocial, environmental, and developmental predictors of substance use. Data were extracted and analyzed thematically to identify recurring patterns and gaps.

Results

Findings revealed that adolescent substance use in Nigeria is shaped by emotional neglect, peer pressure, family dysfunction, socioeconomic hardship, and weak institutional support. Most studies (86.4%) used cross-sectional designs and focused on mixed substances (59.1%). Alcohol use ranged from 30.6% to 82.5%; tobacco from 5.5% to 35.3%. Early initiation, often before age 15, was common. Mental health outcomes appeared in 68.2% of studies, and several supported the self-medication hypothesis. Longitudinal and multi-level approaches were notably lacking.

Conclusion

The review highlights the urgent need for comprehensive, multi-factorial research on adolescent substance use in Nigeria. Future studies should adopt integrative models that account for developmental trajectories, psychosocial stressors, and environmental contexts. Strengthening regulatory frameworks and early intervention programs is essential to mitigate long-term health consequences and reduce the burden of substance use disorders in this vulnerable population.

Keywords

Adolescent substance use risky behaviour psychosocial predictors peer influence self-medication hypothesis mental health early initiation public health intervention

Downloads

Download data is not yet available.

References

  1. Abbani, A.Y., (2021). Nigeria’s demographic transition and implications on the attainment of sustainable development goals. Global Journal of Social Sciences, 20(1), pp.1-10.
  2. Aboagye, R.G., Ahinkorah, B.O., Donkoh, I.E., Okyere, J. and Yaya, S., (2025). A nonlinear decomposition analysis of the rural-urban disparities in tobacco use among women in sub-Saharan Africa. Plos one, 20(9), p.e0331738.
  3. Addo, I.Y., Acquah, E., Nyarko, S.H., Dickson, K.S., Boateng, E.N. and Ayebeng, C., (2024). Exposure to pro-tobacco and anti-tobacco media messages and events and smoking behaviour among adolescents in Gambia. BMC Public Health, 24(1), p.1041.
  4. Adesola, R.O., Opuni, E., Idris, I., Okesanya, O.J., Igwe, O., Abdulazeez, M.D. and Lucero-Prisno III, D.E., (2024). Navigating Nigeria’s health landscape: population growth and its health implications. Environmental health insights, 18, p.11786302241250211.
  5. Akpan, U.U., Olojo, M.O., Oni, T.I., James, E. and Onoja, A., (2024). Assessment of the prevalence and factors contributing to drug and alcohol use among young people in South-South, Nigeria. Int J Sci Health Res, 9(2), pp.352-62.
  6. Akunna, G.G. and Lucyann, C.A., (2023). Nigeria’s War Against Drug Abuse: Prevalence, Patterns, Ramifications, Policy and Multisectoral Response, Strategies and Solutions. Studies in Social Science & Humanities, 2(10), pp.35-55.
  7. Asiyanbi, M., Omopo, O.E., Offor, D.O. and Ilori, K.M., (2025). Substance Abuse among Out-of-School Adolescents: Examining the Roles of Peer Pressure, Self-Esteem, Social Rejection, and Parental Monitoring in Ibadan, Nigeria. Islamic University Journal of Social Sciences, 4(4), pp.1-13.
  8. Brennan, M.M., Corrigan, C., Mongan, D., Doyle, A., Galvin, B., Nixon, E., Zgaga, L., Smyth, B.P., Ivers, J.H. and McCarthy, N., (2024). Predictors and outcomes of adolescent alcohol and drug use: a scoping review. https://doi.org/10.1093/eurpub/ckae144.594
  9. Davids, H.L., Roman, N.V. and Rich, E.G., (2022). Peer pressure and social acceptability between hookah pipe users and non-users among a sample of South African adolescents. South African Journal of Child Health, 16(3), pp.139-145.
  10. Ekpenyong, M.S., Jagun, H., Stephen, H.A., Bakre, A.T., Odejimi, O., Miller, E., Nyashanu, M. and Bosun-Arije, S.F., (2024). Investigation of the prevalence and factors influencing tobacco and alcohol use among adolescents in Nigeria: A systematic literature review. Drug and alcohol dependence, 256, p.111091.
  11. Jacobs, W., Amuta-Jimenez, A.O., Olusanya, O.A., Bristow, A.F., Adeloye, D., & Barry, A.E. (2020). Socio-Ecological Factors of Adolescent Substance Use in Nigeria: A Systematic Review of Literature. Journal of Health Care for the Poor and Underserved 31(4), 1765-1784. https://dx.doi.org/10.1353/hpu.2020.0131.
  12. Liau, C.H., (2022). Consumer Behaviour: Efficacy of Anti-Smoking Initiatives on Continuance by Young Adults in Australia (Doctoral dissertation, Victoria University).
  13. Malami, K., Alkanchi, N. A., Ajibade, B.I., Sarkingobir, K., Binji, A.H., Muhammad, B.S., Oyewumi, Z. and Yusuf, H.A. (2025). Determinants of Substance Abuse Among Youth in Kanwuri Area of Sokoto Metropolis. Sahel Journal of Life Sciences FUDMA, [online] 3(2), pp.390–398.
  14. Mensah, E.O., (2021). To be a man is not a day’s job: The discursive construction of hegemonic masculinity by rural youth in Nigeria. Gender issues, 38(4), pp.438-460.
  15. Menyaga, A.C. and Inongha, N.O., 2025. Uses of Psychological Coping Mechanisms and Resilience in Curbing Insecurity and Out-of-School Problems in Kogi State, Nigeria. Journal of Theoretical and Empirical Studies in Education, 10(1), pp.18-32.
  16. Morojele, N.K., Ramsoomar, L., Dumbili, E.W. and Kapiga, S., (2021). Adolescent Health Series–Alcohol, tobacco, and other drug use among adolescents in sub‐Saharan Africa: A narrative review. Tropical Medicine & International Health, 26(12), pp.1528-1538.
  17. Nabyonga-Orem, J., Asamani, J.A. and Olu, O., (2024). Why are African researchers left behind in global scientific publications?–A viewpoint. International journal of health policy and management, 13, p.8149.
  18. National Heart, Lung, and Blood Institute. (2014). Quality Assessment Tool for Observational Cohort and Cross-Sectional Studies. National Institutes of Health. Available at: https://www.nhlbi.nih.gov/health-topics/study-quality-assessment-tools, (Accessed: 01 October 2025).
  19. Nduka, U.C., Udo, D.I., Medinah, S.A. and Emenike, C.V., (2024). The effect of drug abuse among adolescents in Nigeria: A case study of Gwagwalada, Area Council, Abuja, Nigeria. World J Adv Res Rev, 24(1), pp.299-305.
  20. Ojo, T.F., Agboola, E.B. and Kukoyi, O.B., (2022). Family factors and psychoactive substance use among adolescents in Nigeria. In Families in Nigeria: Understanding their diversity, adaptability, and strengths (pp. 87-98). Emerald Publishing Limited.
  21. Oritsemuelebi, B., Ben-Azu, B., Ordinioha, B., Asiwe, J.N., Chidebe, E.O., Ivie, I.P., Ijirigho, B. and Oghenerukevwe, T., 2025. Prevalence and Determinants of Recreational Drug Use and Related Health Effects Among Youths. Emerging Trends in Drugs, Addictions, and Health, p.100180.
  22. Oweibia, M., Egberipou, T., Timighe, G.C., Ogbe, P.D., Elemuwa, U.G. and Wilson, T.R., (2025). DRUG ABUSE IN NIGERIA; THE PUBLIC HEALTH IMPACT OF COLLECTIVE ACTIONS AND INACTIONS: A SYSTEMATIC REVIEW. medRxiv, pp.2025-05.
  23. Shafie, A.A.H., (2024). Exploring Protective And Risk Factors Among Youth In High-Risk Areas. Educational Administration: Theory and Practice, 30(5), pp.11922-11938.
  24. Shuaibu, H.O., Abdul Rahman, H. and Zulkefli, N.A.M., 2024. Prevalence, risk and protective factors of substance use amongst adolescents living in peri‐urban communities in Abuja, Nigeria. Infant and Child Development, 33(3), p.e2485.
  25. World Health Organization. (2025). Global Report on Trends in Tobacco Use 2000–2024 and Projections 2025–2030. Available at: https://www.who.int/publications/i/item/9789240116276, (Accessed: 3 November 2025)
  26. World Health Organization. (2025). Tobacco Fact Sheet (Updated June 25, 2025). Available at: https://www.who.int/news-room/fact-sheets/detail/tobacco, Available at: (Accessed: 3 November 2025)
  27. World Health Organization. (2025). WHO Tobacco Trends Report (October 6, 2025), Available at: https://www.who.int/news/item/06-10-2025-who-tobacco-trends-report-1-in-5-adults-still-addicted-to-tobacco, (Accessed: 3 November 2025)
  28. Young, A.M., Moji, M., Duby, Z., Tenza, S., Atujuna, M., Palanee-Phillips, T., Minnis, A.M. and Montgomery, E.T., (2025). The “Ideal Man”: How Gender Norms and Expectations Shape South African Men’s Masculinity, Sexual Identities, and Well-Being. The Journal of Men’s Studies, 33(2), pp.417-440.
CONTINUE EXPLORING

Most read articles by the same author(s)

Explore other published research by the authors of this article.

JOURNAL ARTICLE 2026

Knowledge of Avoidable Risk Factors of Hypertension and Their Association with Hypertension Status Among University Students in The United Kingdom

Freedom Nwakaego Igheghe, Kennedy Oberhiri Obohwemu,, Celestine Emeka Ekwuluo, Tina Puri, Gordon Mabengban Yakpir, Chika Oguguo, Kenneth Oshiokhayamhe Iyevhobu, Maame Ama Owusuaa-Asante, Efe Clement Abel, Kingsley Chike Madubuike, Mary Oluwayemisi Akadiri, Leonard Nnamdi Meruo, Chisom Lucky Emeka, Jennifer Adaeze Chukwu, Abba Sadiq Usman, Jerry Soni, Chinaza Amalachukwu Emegoakor, , Barth Onyekachi Nwokedi, David Samuel Otu, Tiphonas Moses Omale, Nneka Gloria Anazodo, Eke Desmond Onyebuchukwu, Ekenedilichukwu Anselem Odiegwu, Nwora Chinonso Oli, Orevaoghene Precious Edewor, Bassey Etim Ekpo-Bassey, Akeem Omokide
PUBLISHED IN The American Journal of Medical Sciences and Pharmaceutical Research Vol. 8 No. 03 (2026): Volume 08 Issue 03
View Article
JOURNAL ARTICLE 2026

Histological Spectrum and Classification of Gastric and Gastro-Oesophageal Junction Cancers in South-East Nigeria: A Retrospective Study

Kenechi Gerald Ike, Ndukwe Chinedu, Ezejiofor Ifeoma Florence, Kingsley Chike Madubuike, Kennedy Oberhiri Obohwemu, Gordon Mabengban Yakpir, Chika Oguguo, Celestine Emeka Ekwuluo, Kenneth Oshiokhayamhe Iyevhobu, Maame Ama Owusuaa-Asante, Efe Clement Abel, Oluwafemi Emmanuel Ooju, Mary Oluwayemisi Akadiri, Leonard Nnamdi Meruo, Chisom Lucky Emeka, Jennifer Adaeze Chukwu, Abba Sadiq Usman, Jerry Soni, Barth Onyekachi Nwokedi, David Samuel Otu, Tiphonas Moses Omale, Nneka Gloria Anazodo, Eke Desmond Onyebuchukwu, Ekenedilichukwu Anselem Odiegwu, Chinaza Amalachukwu Emegoakor, Chidinma Onyinye Emegoakor, Nwora Chinonso Oli, Orevaoghene Precious Edewor, Bassey Etim Ekpo-Bassey, Akeem Omokide, Favour Nkami Eyong
PUBLISHED IN The American Journal of Medical Sciences and Pharmaceutical Research Vol. 8 No. 03 (2026): Volume 08 Issue 03
View Article
JOURNAL ARTICLE 2026

Low Prevalence of Carbapenemase Gene NDM-1 in Uropathogenic Klebsiella pneumoniae and Escherichia coli: A Molecular Surveillance Study

Chinaza Maria Ozuluoha, Moses Nkechukwu Ikegbunam, Celestine Emeka Ekwuluo, Kennedy Oberhiri Obohwemu, , Kenneth Oshiokhayamhe Iyevhobu, Abba Sadiq Usman, Samuel Sam Danladi, Oladipo Vincent Akinmade, Christabel A. Ovesuor, Aliyou Moustapha Chandini, Jennifer Adaeze Chukwu
PUBLISHED IN The American Journal of Medical Sciences and Pharmaceutical Research Vol. 8 No. 01 (2026): Volume 08 Issue 01
View Article
JOURNAL ARTICLE 2026

Strengthening Infectious Disease Surveillance in Nigeria: A Focused Scoping Review of SORMAS and the Electronic Integrated Disease Surveillance and Response System

Ayodele Israel Ajayi, Oluwafemi Emmanuel Ooju, Kennedy Oberhiri Obohwemu, Celestine Emeka Ekwuluo, Gordon Mabengban Yakpir, Kenneth Oshiokhayamhe Iyevhobu, Daniel Ikechukwu Oseji, Oluwakemi Laguda-Akingba, Eddy Eidenehi Esezobor, Nera Perpetual Kadiri-Eneh, Obiageli Uzoamaka Onyemelukwe, Oladipo Vincent Akinmade, Solomon Atuman, Chisom Lucky Emeka, Chinenye Cynthia Akwolu, Abidemi Aminat Ekunsumi, Bamidele Julius Ajala, Adah Michael Ameh, Adeola Ebunoluwa Efuntoye, Phina Chinelo Ezeagwu, Peace Ogochukwu Daniel-Clement
PUBLISHED IN The American Journal of Medical Sciences and Pharmaceutical Research Vol. 8 No. 08 (2026): Volume 08 Issue 08
View Article