Articles
| Open Access |
DOI: Current Views On The Pathogenesis Of The Parietal-Visceral Pathway Of Gastric Cancer Metastasis
Mirdjalol Dehkanovich Djuraev , Doctor Of Medical Sciences, Professor, Head Of The Department Of Oncology, Samarkand State Medical Institute, Uzbekistan Nodir Maxammatkulovich Rahimov , Doctor Of Medical Sciences, Associate Professor, Department Of Oncology, Samarkand State Medical Institute, Uzbekistan Mavluda Nigmatovna Karimova , Doctor Of Philosophy In Medical Sciences (PhD), Associate Professor At The Department Of Oncology, Samarkand State Medical Institute, Uzbekistan Shakhnoza Shavkatovna Shakhanova , Assistant In The Department Of Oncology, Samarkand State Medical Institute Samarkand Branch Of The Republican Specialized Scientific And Practical Medical Centre, UzbekistanAbstract
Metastases to the peritoneum occur in 55-60% of patients with gastric cancer and are associated with a 5-year overall survival of 2%. Treatment options for these patients are limited, and targeted therapy or immunotherapy is not available. Rational therapeutic targets have yet to be found.In this review, we present the published literature and our own recent experience in molecular biology to identify important molecules and signalling pathways as well as cellular immunity involved in GC peritoneal metastases.
Keywords
Gastric cancer, chromosomal abnormalities, immunology, molecular biology, peritoneal carcinomatosis, peritoneal metastases, visceral metastasis
References
Akhmedov R.M., Mirkhojaev I.A., Khamdamov B.Z. Morphostructural changes in the liver in the elderly and old age // Conference proceedings. Journal of Problems of Biology and Medicine. - 2016. - №3,1(90). - С. 18.56.
Azimov M. I., Shomurodov K.E. A technique for Cleft Palate Repair. Journal of research in health science. Vol. 1, No. 2, 2018, pp. 56-59
Bollen, L., Jacobs, W.C.H., Van der Linden, Y.M. et al. A systematic review of prognostic factors predicting survival in patients with spinal bone metastases. Eur Spine J 27, 799-805 (2018). https://doi.org/10.1007/s00586-017-5320-3
Crawford, E.D., et al., Challenges and recommendations for early identification of metastatic disease in prostate cancer. Urology, 2014.83 (3): p. 664-9.
Lipton, A. The Science and Practice of Bone Health in Oncology: Managing Bone Loss and Metastasis in Patients With Solid Tumors / A. Lipton // J. Nat. Compr. Canc. Netw. - 2009. - Vol. 7. - P. 1-29
F Ruatta, L Derosa, B Escudier, E Colomba, A Guida, G Baciarello, Y Loriot, K Fizazi, L Albiges, European Journal of Cancer. Prognosis of Renal Cell Carcinoma With Bone Metastases: Experience From a Large Cancer Center Eur. J. Cancer 2018 Dec 11; 107 (xx) 79-85
G. M. HODJIMATOV, K. K. MIRZAEV, D. T. AZIZOV. PHARMACOKINETICS OF ANTIBIOTICS IN EXPERIMENTAL GUNSHOT WOUNDS. A Multidisciplinary Peer Reviewed Journal Research for Revolution ISSN No-2581 – 4230,Is Published Online in Volume-7, Issue2, Feb. – 2021,pp120-123
G. M. HODJIMATOV, Kh. Kh. Hamdamov. DIAGNOSTICS AND TREATMENT OF CHOLEDOCHOLITIASIS IN ELDERLY AND SENILE AGE PATIENTS // European Journal of Research Development and Sustainability (EJRDS) Available Online at: https://www.scholarzest.com Vol. 2 No. 3, March 2021, ISSN: 2660-5570
Kamalova M. I., Islamov Sh. E., Khaydarov N.K.// MORPHOLOGICAL CHANGES IN BRAIN VESSELS IN ISCHEMIC STROKE. Journal of Biomedicine and Practice 2020, vol. 6, issue 5, pp.280-284
Khamdamov B.Z. Indicators of immunocitocine status in purulent-necrotic lesions of the lover extremities in patients with diabetes mellitus.//American Journal of Medicine and Medical Sciences, 2020 10 (7) 473-478 DOI: 10.5923/j.ajmm.2020.- 1007.08
Musaev U.Y.,Rizaev J.A., Shomurodov K.E. New views on the problem of dysemryogenesis stigmas of dento-mandibular and facial system from the position of their formation in the disability of the population // Central Asian Scientific and Practical Journal "Stomatologiya "2017.-#3-(68).-P.9-12.
Tillyashaikhov MN, Yusupov Sh. Kh., Boyko EV, Valieva RM Criteria for choosing hormonal therapy for patients with advanced prostate cancer // Bulletin of the Tashkent Medical Academy. - 2016. - No. 2 (05). - S. 95–97
Tillyashaikhov MN, Rakhimov NM, Tillyashaikhova RM Evolution of views on the diagnosis and treatment of renal cell cancer // Medical Journal of Uzbekistan. - Tashkent, 2018.- №4. - S. 51-55.
Tillyashayakhov M. N., Rahimov N. M., Tillyashayakhova R. M. Long-term results of modified surgical access to regional lymph nodes and main vessels in the treatment of renal cell carcinoma // The USA Journals Volume 03 Issue 02-2021 174 The American Journal of Medical Sciences and Pharmaceutical Research (ISSN – 2689-1026) Published: February 28, 2021 | Pages: 161-174 Doi: https://doi.org/10.37547/TAJMSPR/Volume03Issue02-24
: Rahimov N, Shakhanova Sh. Development of new approaches in treatment of metastatic renal cell carcinoma // Journal of research in health science Volume 5-6 issue. 4 2020, pp. 82-95 ISSN 2523-1251 (Online), p 82-95.
Saidkulov B, Abduraxmonov A, Rahimov N. Recurrent ovarian cancer: mechanisms of development of peritoneal malignant ascites //. European Journal of Molecular & Clinical Medicine ISSN 2515-8260 Volume 7, Issue 2, 2020, p 2423-2428
Shakhanova Sh.Sh., Djuraev M.D., Rakhimov N.M., Karimova M.N., Asatulayev A.F., (2021). Determination Of Risk Parameters In The Detection Of Asymptomatic Bone Metastases Of Kidney And Prostate Cancer. The American Journal of Medical Sciences and Pharmaceutical Research, 3(02), 161-174.
Ziyadullaev Sh, Elmamatov O, F Raufov Cytogenetic and immunological alterations of recurrent bladder cancer // European Journal of Molecular & Clinical Medicine 2020, Volume 7, Issue 2, p 1877- 1883.
Article Statistics
Copyright License
Copyright (c) 2021 The American Journal of Medical Sciences and Pharmaceutical Research
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors retain the copyright of their manuscripts, and all Open Access articles are disseminated under the terms of the Creative Commons Attribution License 4.0 (CC-BY), which licenses unrestricted use, distribution, and reproduction in any medium, provided that the original work is appropriately cited. The use of general descriptive names, trade names, trademarks, and so forth in this publication, even if not specifically identified, does not imply that these names are not protected by the relevant laws and regulations.