Inflammatory pathology of the ENT organs accounts for 87% of all visits to the otorhinolaryngologist, in the last decade the incidence of paranasal sinusitis (PNS) has increased, and the proportion of hospitalized patients with this pathology has increased almost 3 times every year. The problem of timely diagnosis and treatment of PNS is currently quite relevant, despite the emergence of new modern methods of conservative and surgical treatment. According to various authors, PNS currently ranks first among inflammatory diseases of the upper respiratory tract. The paranasal sinuses (SNS) are a single morphological and functional system with similar etiological factors and mechanisms for the development of diseases, therefore, when studying the epidemiology of the PNS, it is necessary to assess the prevalence of diseases not only of each sinus separately, but also of their combined lesions.

Inflammation, rhinosinusitis

Botirov A. J. et al. Clinical and morphological results of xenografts to use in myringoplasty //The International Tinnitus Journal. – 2020. – Т. 24. – №. 1. – С. 1-6.

Djuraev J. A. et al. Distribution of Allel Variants and Genotypes of Il4, Il10, Il12b, Tlr2 Genes in the Group of Patients with CPRS //Annals of the Romanian Society for Cell Biology. – 2021. – С. 4466-4470.

Ходжанов, Ш. Х., Джураев, Ж. А., Ахунджанов, Н. А., & Ботиров, А. Ж. (2020). CLINICAL AND MORPHOLOGICAL CHARACTERISTICS OF ANTHROCHANAL POLYPS. Uzbek medical journal, 6(1).

Makhsitaliev, M. (2021). The Functional State Of The Mucous Membrane Of The Nasal Cavity And Paranasal Sinuses After Radical And Minimally Invasive Surgical Interventions. The American Journal of Medical Sciences and Pharmaceutical Research, 3, 31-40.

Хакимов, A. M., Ходжаев, А. И., & Ахунджанов, Н. А. (2002). Состояние вестибулярной функции у больных с доинсультными формами цереброваскулярных расстройств на фоне артериальной гипертензии. Российская оториноларингология, (3), 62.

Ахунджанов Н. А. Состояние остроты слуха у больных с гипертонической болезнью на фоне гипотензивной терапии //Ўзбекистон республикаси оториноларингологларнинг iy съездига бағишланган маҳсус сон. – С. 47.

Хасанов, У. С., Вохидов, У. Н., & Джураев, Ж. А. (2018). Состояние полости носа при хронических воспалительных заболеваниях носа и околоносовых пазух у больных с миокардитом. European science, (9 (41)).

Djuraev, J. A., Khasanov, U. S., Vohidov, U. N., & Sharipov, S. S. (2020). Results of Allergological and Immunological Research in Patients with Polipoid Rhinosinusitis. Asian Journal of Immunology, 34-40.

Normurodov, B. K., Djuraev, J. A., Shaumarov, A. Z., & Akhmedov, J. M. (2020). Prevalence and structure of purulent inflammatory diseases of the maxillofacial area. Central Asian Journal of Medicine, 2020(1), 116-130.

Khasanov, U. S., & Djuraev, J. A. (2020). Morphological characteristics of chronic polypous rhinosinusitis. CUTTING EDGE-SCIENCE, 30.

Djuraev, J. A., & Khasanov, U. S. (2021). Results of Frequency Analysis Distribution of Polymorphism Rs1800895 592c> A In Il10 Gene among Patients with Chronic Polypoid Rhinosinusitis. International Journal Of Medical Science And Clinical Research Studies, 1(6), 129-134.

Djuraev, J. A., Khasanov, U. S., Botirov, A. J., & Shaumarov, A. Z. (2020). Results of an immunogistochemical study in patients with polipoid rhinosinusitis. European Journal of Molecular & Clinical Medicine, 7(2), 2526-2541.

Djuraev, J. A., Khasanov, U. S., & Vokhidov, U. N. (2018). The prevalence of chronic inflammatory diseases of the nose and paranasal sinuses in patients with myocarditis. European Science Review, (5-6), 147-149.

Djuraev, J. A. Prevalence of Allelic and Genotypic Variants of Il4, Il10, Il12b and Tlr2 Gene Polymorphism in Patients with Chronic Polypoid Rhinosinusitis.

Jumanov, D. A. U., Bakieva, S. K., Djuraev, J. A., Kudiyarov, I. A., & Djabbarov, N. N. (2021). International Journal of Biological and Pharmaceutical Sciences Archive. International Journal of Biological and Pharmaceutical Sciences Archive, 1(1), 011-015.

Shaumarov, A. Z., Shaikhova, H. E., Normurodov, B. K., Akhmedov, S. E., & Djuraev, J. A. (2021). Role of Hemostatic Agents in Simultaneous Surgical Interventions in the Nasal Cavity. Journal of Experimental and Clinical Surgery, 14(2), 175-180.

UN, Khasanov US Djuraev JA Vokhidov, and A. J. Botirov. "Frequency analysis results distribution of C589T rs2243250 polymorphism in IL4 gene among patients with chronic rhinosinusitis." (2021).

Nordjigitov, F. N., & Djuraev, J. A. (2021). RESULTS OF MORPHOLOGICAL STUDIES OF VARIOUS FORMS OF CHRONIC TONSILLITIS. Central Asian Journal of Medicine, 2021(4), 125-132.

Khasanov, U. S., Djuraev, J. A., Vokhidov, U. N., Khujanov, S. K., Botirov, A. Z., & Shaumarov, A. Z. (2022). RESULTS OF FREQUENCY ANALYSIS DISTRIBUTION OF A1188C RS3212227 POLYMORPHISM IN THE IL 12B GENE AMONG PATIENTS WITH CHRONIC RHINOSINUSITIS POLYPOSIS. Oriental Journal of Medicine and Pharmacology, 2(01), 104-115.

Khasanov, U. S., Khaydarova, G. S., Rakhimjonova, G. A., & Djuraev, J. A. (2022). METHOD FOR THE TREATMENT OF EXUDATIVE OTITIS MEDIA IN CHILDREN. Oriental Journal of Medicine and Pharmacology, 2(01), 64-81.

Khasanov, U. S., Abdullaev, U. P., & Djuraev, J. A. (2022). RESULTS OF AUDIOLOGICAL EXAMINATION IN ACUTE SENSORINEURAL HEARING LOSS OF VARIOUS GENESIS. Oriental Journal of Medicine and Pharmacology, 2(01), 24-50.