The reactions of vigorous heterotrophic soil microorganism local area to entirely unexpected centralizations of different amalgams, in particular, mercury, nuclear number 30 and nickel were researched. The huge combinations were added to soil at the level of fifty, 100, 200, 300 and 500 μg/g of soil, severally. The dirt examples were hatched for 28 days all through that all out oxygen consuming heterotrophic microorganism counts were taken irregularly. The outcomes incontestible that the extension of microorganism showed reactions that were subject to the kind of amalgam and level of fixations. Mercury at the centralization of 300 and 500 μg/g soil, controlled development of the microorganism by the twenty eighth day of the review while for nickel, development hindrance on the twenty eighth day happened for the 500 μg/g. Be that as it may, for zinc, there was no finished restraint of development all through the exploratory sum at all amalgam fixations. Decrease in microorganism populace and loss of microorganism variety is clear as compound fixation expanded.