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Scalable Vulnerability Management and Automated Threat Mitigation in Healthcare Ecosystems: An Analysis of AI-Driven Frameworks for 100K+ Asset Environments

Lina R. Al-Shaqiri , Independent Researcher, Interdisciplinary Innovations in Patient-Centric Cyber Safety & Asset Governance, Amman, Jordan

Abstract

The rapid digitization of healthcare infrastructure has precipitated a critical security challenge: the management of vulnerabilities across massive, heterogeneous environments often exceeding 100,000 assets. This paper investigates the efficacy of Artificial Intelligence (AI) and automated frameworks in mitigating cyber threats within these high-density clinical ecosystems. By analyzing recent breach statistics and contrasting legacy security models with modern cloud-based remediation tools, we evaluate the operational shift required to secure the Internet of Medical Things (IoMT). The methodology employs a comparative analysis of manual versus AI-driven vulnerability management cycles, focusing on metrics such as Mean Time to Remediate (MTTR) and false positive rates. Our analysis draws upon legal frameworks and industrial big data analytics to contextualize the technical findings within the broader scope of international governance and compliance. The results indicate that while legacy models fail to scale, AI-driven automated threat mitigation significantly reduces the window of exposure for critical clinical assets. However, the integration of these technologies introduces complex legal and ethical considerations regarding data privacy and algorithmic accountability. We conclude that a hybrid approach, combining automated "self-healing" networks with robust human oversight, is essential for the future resilience of healthcare information systems.

Keywords

Vulnerability Management, Healthcare Cybersecurity, Artificial Intelligence, Automation

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Lina R. Al-Shaqiri. (2025). Scalable Vulnerability Management and Automated Threat Mitigation in Healthcare Ecosystems: An Analysis of AI-Driven Frameworks for 100K+ Asset Environments. The American Journal of Interdisciplinary Innovations and Research, 7(11), 71–77. Retrieved from https://theamericanjournals.com/index.php/tajiir/article/view/6952