This study presents a hematological evaluation of medically managed cases of pyometra in dogs. Pyometra, a common reproductive disorder in intact female dogs, can lead to life-threatening complications if left untreated. The study investigates the hematological parameters in dogs diagnosed with pyometra and treated medically, aiming to assess the effectiveness of medical management in improving hematological profiles. Hematological parameters such as white blood cell count, red blood cell count, hematocrit, hemoglobin concentration, and platelet count are analyzed before and after medical treatment. Additionally, the study explores correlations between hematological parameters and clinical outcomes in medically managed pyometra cases. The findings provide valuable insights into the hematological changes associated with pyometra and the effectiveness of medical interventions in dogs.