This study explores the impact of integrating mindfulness practices into classroom settings on the well-being and academic success of college students during the COVID-19 pandemic and in the post-pandemic context. With mental health challenges rising among students due to remote learning, isolation, and academic pressures, mindfulness has emerged as a potential solution to enhance emotional regulation, reduce stress, and improve academic outcomes. Through a mixed-methods approach, this research analyzes surveys and interviews conducted with college students who participated in a mindfulness program integrated into their courses. The findings suggest that mindfulness practices contribute to improved emotional well-being, decreased anxiety, and enhanced academic performance. The study also discusses the broader implications for integrating mindfulness in higher education as a means to support student mental health and academic success in an increasingly uncertain world.